乳腺癌保乳术后局部复发影响因素分析  

Influence factors of recurrence of breast cancer after conservative surgery

作　　者：李刚[1] 李峻[1] 罗方鑫 谢玉莲[1] 

机构地区：[1]解放军第458医院乳腺科,广东广州510600

出　　处：《海南医学院学报》2013年第11期1576-1578,共3页Journal of Hainan Medical University

基　　金：中国高校医学期刊临床专项资金项目(112210860)~~

摘　　要：目的：探讨乳腺癌保乳术后局部复发影响因素与预防策略。方法：采用术后紧密跟踪、预约定期回院复查、电话随访等多种方式对2008年9月～2011年9月在我院治疗的300例乳腺癌患者进行临床资料的收集，随访2．5年，根据乳腺癌患者保乳术后局部复发与否将本研究入组患者分为对照组和观察组，分析乳腺癌保乳术后局部复发情况和影响因素。结果：乳腺癌保乳术后局部复发率为5．33％，肿瘤分级高、淋巴结转移数多是保乳术后局部复发的危险因素，年龄、术后规范化疗和术后足程放疗是保乳术后局部复发的保护因素。结论：乳腺癌保乳术后局部复发率较根治性手术稍高，复发受多方面因素影响，应采取针对性的预防干预措施来降低患者的保乳术后局部复发率，改善患者的预后。Objective. To explore the risk factors of local recurrence of breast cancer after breast conserving surgery and prevention strategies. Methods.- Clinical data of 300 breast cancer cases admitted from September 2008 to September 2011 were collected by various ways such as close postoperative follow- up, regular hospital review, random telephone follow-up. The follow-up lasted 2.5 years. According to recurrence patients were divided into control group and observation group, local recurrence and influence factors were analyzed. Results. After conservative surgery local recurrence rate was 5.33 %. Higher tumor grade, lymph node metastasis were the risk factors of local recurrence, while age, standard chemotherapy and enough radiotherapy after surgery were protective factors. Conclusion： Local recurrence of breast canc- er after breast-conserving surgery was slight higher than that of radical surgery. It is influenced by various factors, we should take preventive interventions to reduce the local recurrence rate, and improve the prognosis of the patients.

关 键 词：乳腺癌 保乳术 局部复发 影响因素 横断面调查 

分 类 号：R737.9[医药卫生—肿瘤]