急性低压缺氧对飞行人员血浆乳酸及乳酸脱氢酶含量的影响  

Effects of Acute Hypoxia on Plasma Lactic Acid and Lactic Dehydrogenase Content in Pilots.

作　　者：刘玉[1] 秦世贞[1] 李文斌[1] 

机构地区：[1]海军总医院航空潜水医学中心,北京100037

出　　处：《航天医学与医学工程》2000年第6期414-416,共3页Space Medicine & Medical Engineering

摘　　要：目的探讨急性低压缺氧对飞行人员血浆乳酸 (LA)及乳酸脱氢酶 (LDH)含量的影响。方法用比色法测定了 1 6名健康男性歼击机飞行人员清晨 (6∶0 0a .m .)、急性中度低压缺氧 2 0min后即刻 (1 0∶0 0a .m .)及下降至地面 6h后 (4∶0 0 p .m .)的血浆LA及LDH含量 ,并以 1 6名健康男性地面人员相应时间的测定作对照。结果实验组急性中度低压缺氧 2 0min后即刻 ,血浆LA水平明显高于实验前及实验后 6h ,也高于同一时间对照组 (P <0 .0 1 ) ,实验后 6h时血浆LA含量下降 ,与实验前及同一时间对照组相比较无显著性差异 (P >0 .0 5)。实验组急性中度低压缺氧 2 0min后即刻 ,血浆乳酸脱氢酶含量与实验前及实验后 6h以及同一时间对照组相比均无显著性差异 (P >0 .0 5)。结论急性中度低压缺氧能使飞行人员血浆乳酸水平升高 ,出舱后 6h内恢复正常 ,而LDH无明显变化。Objective To study the effect of acute moderate hypoxia on plasma lactic acid(LA) and lactic dehydrogenase(LDH) content in pilots. Method Concentrations of plasma LA and LDH were measured by colorimetry in 16 healthy male pilots in the early morning(6∶00 a.m.), following acute moderate hypoxic exposure(10∶00 a.m.) and 6 hours after returned to the ground(4∶00 p.m.).16 healthy male ground people served as control group, and their plasma LA and LDH contents were assayed at corresponding time. Result Plasma LA after moderate hypoxic exposure in the pilot group was significantly higher than that at 6∶00 a.m.,4∶00 p.m.,and control group(P<0.01).While the content at 6∶00 a.m.,4∶00 p.m. in pilot group was not significantly different from the control group(P>0.05).The content of plasma LDH after moderate hypoxic exposure in the pilot group was not significantly higher than that at 6∶00 a.m.,4∶00 p.m.,and control group (P>0.05). Conclusion Acute moderate hypoxia can make the plasma LA content increase in pilots,and reach to the normal level within 6 h.While the LDH content has no significantly change.

关 键 词：飞行员 低压 缺氧 乳酸 乳酸脱氢酶 

分 类 号：R852.11[医药卫生—航空、航天与航海医学]