胃肠道间质瘤的腹腔镜手术治疗  

Laparoscopic resection for gastrointestinal stromal tumors

作　　者：张鹏[1] 常伟龙[1] 帅晓明[1] 夏泽锋[1] 蔡开琳[1] 高金波[1] 陶凯雄[1] 王国斌[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院胃肠微创外科,武汉430022

出　　处：《中华普通外科杂志》2013年第11期861-864,共4页Chinese Journal of General Surgery

摘　　要：目的探讨腹腔镜手术治疗胃肠道间质瘤（gastrointestinalstromaltumor，GIST）的临床应用价值及安全性。方法回顾分析华中科技大学同济医学院附属协和医院2005年1月至2010年9月问经腹腔镜手术治疗的35例GIST患者的临床资料。结果本组35例GIST患者中包含胃GIST27例，小肠GIST5例，直肠GIST3例。肿瘤中位直径3cm（0．8—16．0cm）。除1例因肿瘤较大而中转开腹外其余均顺利完成手术，平均手术时间（104±32）min，术中出血量（25±30）ml，排气时间（36±15）h，术后住院（8．4±1．8）d，无手术并发症及死亡病例。中位随访44个月（22～78个月），均未见肿瘤复发或转移。结论对于GIST，特别是直径〈5cm者，行腹腔镜手术治疗安全可靠，术式选择应依据肿瘤大小与位置进行个体化治疗。Objective To evaluate the clinical value and safety of laparoscopic resection for gastrointestinal stromal tumors （GISTs）. Methods A retrospective analysis was made on thirty-five patients who underwent laparoseopie resection for GISTs in Wuhan Union Hospital from January 2005 to September 2010. Results There were 27 gastric GIST cases, 5 intestinal GIST cases and 3 rectal GIST cases. The median tumor size was 3 cm （range 0. 8 - 16. 0 cm ）. All operations were successfully accomplished within （104 ± 32） min except one who was shifted to open surgery for large size of the tumor. The intraoperative blood loss was （ 25 ± 30 ） ml and exhaust time was （ 36 ± 15 ） h. The postoperative hospital stay was （ 8.4 ± 1.8） days. There was no major morbidities nor mortality. During the follow-up time from 22 to 78 months （ median, 44 months）, there were no recurrences or metastasis. Conclusions The low morbidity rate and the long-term disease-free survival indicates that laparoscopic resection for GISTs with diameter of tumor size 〈 5 cm is safe and feasible.

关 键 词：胃肠道间质肿瘤 腹腔镜 

分 类 号：R735[医药卫生—肿瘤]