食管癌术后早期肠内营养治疗的临床研究  

Clinical Study of Postoperative Early Enteral Nutrition for Esophageal Carcinoma

作　　者：王庆淮[1] 吴勋宁[1] 谭宁[1] 滕泽林[1] 蒙伟平[1] 冯健[1] 

机构地区：[1]广西贵港市人民医院胸心外科,537100

出　　处：《实用癌症杂志》2013年第6期636-638,共3页The Practical Journal of Cancer

基　　金：广西贵港市科学研究与技术开发计划项目(贵科攻1004022)

摘　　要：目的探讨食管癌术后早期肠内营养治疗的可行性和临床价值。方法 42例食管癌患者(A组)术中经幽门后至空肠上段留置胃管(鼻空肠管)(EN组),对照组(B组)42例患者未进行肠内营养(PN组)。比较两组患者术后恢复情况、营养支持费用及并发症情况。结果所有食管癌患者术中顺利留置胃管营养管,EN组患者肠鸣音恢复时间、肛门排气时间较PN组明显缩短,体重、人血白蛋白水平术后第7 d、第21 d EN组明显高于PN组(P<0.05);EN组营养支持费用明显减少(P<0.05);术后第7 d外周血淋巴细胞计数EN组明显高于PN组(P<0.05)。结论食管癌患者术后应用胃管在幽门后-空肠上段行早期肠内营养安全可行,可以改善患者营养状况,促进其康复,能减少治疗费用,并发症发生率下降,手术成功率提高,是1种既经济又简单、安全有效的营养支持方法。Objective To investigate the feasibility and clinical application value of postoperative early enteral nutrition in the treatment of the esophageal carcinoma. Methods 42 cases of esophageal carcinoma patients with transpyloric to the jejunum（ naso-jejunal tube indwelling gastric tube ） were group A （group EN）, control group and group B were 42 patients without enteral nutrition（ group PN）o Compare postoperative recovery condition, nutritional support costs and other complications of patients. Results Indwelling gastric feeding tube was successful. The return of bowel sounds, anal exhaust time was obviously shortened in group EN than in group PN ,weight, human serum albumin measurements on postoperative day 7th ,21 st days after operation in group EN were higher than those in group PN （ P 〈 0.05 ） ; nutritkmal support costs significantly in group EN was less （ P 〈 0.05） ; peripheral blood lymphocyte count was higher in group EN than in group PN in the 7th day（ P 〈 0.05 ）. Conclusion Postoperative application of gastric tube in Helicobacter-jejunum enteral nutrition for the patients with esophageal carcinoma is safe and feasible, and can improve the nutritional status, promote the rehabilitation of patients, protect gastrointestinal mucosal barrier function, promote the recovery of gastrointestinal function, improve nutrition, reduce cost, reduce the incidence of complications, and improve the success rate of operation.

关 键 词：食管癌 双胃管 早期肠内营养 肠外营养 术后并发症 

分 类 号：R735.1[医药卫生—肿瘤]