补肾活血化痰汤和尼莫地平治疗血管性认知障碍的对比研究  

Case-control Study on the Treatment of Vascular Cognitive Impairment between Bushenhuoxuehuatan Decoction and Nimodipine

作　　者：颜冬润 余恒旺 黄文国 黎治荣 

机构地区：[1]广东省茂名市中医院,广东茂名525000

出　　处：《中国中医急症》2013年第11期1855-1856,共2页Journal of Emergency in Traditional Chinese Medicine

基　　金：广东省中医药局建设中医药强省科研项目(2009098)

摘　　要：目的通过观察补肾活血化痰汤在治疗血管性认知障碍患者的疗效。方法将40例血管性认知障碍患者随机分为两组,治疗组口服补肾活血化痰汤合尼莫地平治疗,对照组口服尼莫地平治疗,疗程8周,使用MMSE量表对患者进行认知功能测评。结果治疗组总有效率高于对照组;两组治疗后MMSE评分明显升高(P<0.01),治疗后治疗组评分明显高于对照组(P<0.05)。结论补肾活血化痰汤和尼莫地平均能较好缓解血管性认知障碍患者的临床症状,但补肾活血化痰汤配合尼莫地平的治疗效果优于单纯使用尼莫地平治疗。Objective： To observe the treatment of Bushenhuoxuehuatan Decoction in the Vascular Cognitive Impairment,evaluate the clinical efficacy of Bushenhuoxuehuatan Decoction in the Vascular Cognitive Impair- ment. Methods： All 40 Vascular Cognitive Impairment patients were randomly divided into two groups：the treat- ment group in which 20 cases and the control group in which 20 cases. The treatment group was treated with Ni- modipine and Bushenhuoxuehuatan Decoction,the control group was treated with Nimodipine. The two groups were treat for 8 weeks. MMSE was used for the assessment of cognitive function. Results： The effective rate of the treatment group was significantly higher than the control group. After treatment,the MMSE scores of two groups were significantly higher than before treatment （P〈 0.01 ）,the treatment group score was significantly higher than the control group （P 〈 0.05）. Conclusion： Bushenhuoxuehuatan Decoction and Nimodipine can better alleviate Vascular Cognitive Impairment in patients with clinical symptoms,but Bushenhuoxuehuatan Decoction with Ni- modipine treatment is better than simply using Nimodipine.

关 键 词：血管性认知障碍 补肾活血化痰法 尼莫地平 

分 类 号：R743[医药卫生—神经病学与精神病学]