nm23基因及其在食管癌预后监测中的研究进展  

Relationship between the nm23 gene and prognosis of esophageal carcinoma

作　　者：侯建章[1] 冯婧[2] 侯振江[1] 

机构地区：[1]沧州医学高等专科学校,河北省沧州市061001 [2]沧州市中心医院,河北省沧州市061001

出　　处：《世界华人消化杂志》2013年第31期3356-3362,共7页World Chinese Journal of Digestology

摘　　要：食管癌的发生、发展是多基因相互作用的共同结果,nm23(nonmetatasis23)基因参与肿瘤细胞转移的调节,具有抑制肿瘤淋巴转移的作用,检测nm23基因的变化,可预测食管癌是否具有淋巴结转移,也是监测其预后的重要指标.The occurrence and development of esophageal cancer are the result of multiple gene interac- tions, and the nm23 gene is involved in the regulation of tumor cell metastasis and can in- hibit lymph node metastasis. The detection of the change in the nm23 gene can help predict the presence of lymph node metastasis or not in esophageal carcinoma. Moreover, nm23 is an important indicator for prognosis evaluation in esophageal carcinoma.

关 键 词：NM23基因 食管癌 预后监测 

分 类 号：R735.1[医药卫生—肿瘤]