吲哚美辛微生物及自然光降解研究  

Microbial and sunlight degradation of indomethacin

作　　者：张婷[1] 吴波[1] 孙娜[1] 陈怀侠[1] 

机构地区：[1]湖北大学化学化工学院,湖北武汉430062

出　　处：《湖北大学学报（自然科学版）》2013年第4期441-444,448,共5页Journal of Hubei University：Natural Science

基　　金：国家自然科学基金(20975030)资助

摘　　要：药品与个人护理品（PPCPs）是一类新型环境微污染物，由于其“假”持久性而受到广泛的关注．微生物和光化学降解是这类物质在自然环境中的主要消减途径．以武汉地区春季太阳光为光源，引入固相萃取方法研究低浓度吲哚美辛在自然环境中的微生物及自然光降解．考察吲哚美辛固相萃取条件，以及不同浓度、基质（Cl-、HCO3-、NO3-、Fe3＋、腐植酸）及共存物（萘普生、呋喃唑酮）对吲哚美辛光降解的影响．实验结果表明，吲哚美辛在东湖水中微生物降解速率较快，而在长江水中降解很微弱．浓度范围为1-500μg／L时吲哚美辛的光降解速率常数（k）与浓度（C）成指数函数．Pharmaceutical and personal care products （PPCPs） are late-model micropol lutants, they had been made acute concern due to their pseudopersisten. Photodegradation of this compounds caused by sun irradiation may be of major significance in the natural elimination process. In this work, solid-phase extraction was used to study the microbial and sunlight（Wuhan, spring） degradation of indometacin in surface water. The effects of different parameters such as water quality, pH, initial concentration, familiar ions（Cl-, HCO3-, NO3-, Fe3＋, HA） and coexisting compounds（furazolidone, naproxen） on photodegradation of indometacin had been studied. The result showed that microbial degradation in east lake water was significant but neglect in Changjiang River water; when the concentration ranges 1--500μg/L correlation between the degradation rate and concentration exactly filed the exponential function.

关 键 词：PPCPS 吲哚美辛 自然光降解 微生物降解 固相萃取 

分 类 号：O655[理学—分析化学]