非酮症高血糖性偏侧舞蹈症临床及影像分析  

Clinical and neuroimaging analysis of 4 patients with hemichorea associated with non-ketotic hyperglycaemia( HC-NH)

作　　者：刘慧勤[1] 姚勇[1] 张杰文[1] 张健[1] 

机构地区：[1]河南省人民医院神经内科,郑州450003

出　　处：《医药论坛杂志》2013年第12期49-51,54,共4页Journal of Medical Forum

摘　　要：目的探讨非酮症高血糖性偏侧舞蹈症的临床特征及影像学表现。方法对2011年1月—2013年3月连续住院的4例非酮症高血糖性偏侧舞蹈症患者的临床及影像学资料进行回顾性分析。结果 4例非酮症高血糖性偏侧舞蹈症患者均为绝经期女性;1例临床表现为四肢舞蹈样症状,但影像学未见异常;1例单侧舞蹈样症状,但影像学见双侧基底节受累;各例MRI序列间表现出不匹配现象。结论高血糖渗透性所致代谢紊乱可能较血管功能不全在非酮症高血糖性偏侧舞蹈症病理机制中起更重要作用。Objective To investigate the clinical characteristic and imaging features of hemichorea associated with non - ketotic hyperglycaemia（ HC - NH）. Methods Clinical and neuroimaging features of four consecutive patients of HC - NH hospitalized during period of time from January 2011 to March 2013 were retrospectively analyzed. Results All of the four HC - NH patients are post - menopause women; One case expressed bilateral hemichorea, but neuroimaging was normal; the other case expressed one side hemichorea, but neoroimaging show both basal ganglia abnormal signals; And MRI series of each case showed mismatch phenomenon. Conclusion The metabolic derangements associated with hyperglycemia maybe play a more important role than vascular insufficiency in the pathomeehanism of HC - NH.

关 键 词：非酮症高血糖性偏侧舞蹈症 影像学 不匹配 代谢紊乱 

分 类 号：R742.2[医药卫生—神经病学与精神病学]