颈段椎管内外哑铃形节细胞神经瘤1例报告并文献复习  

Intra-and extra-spinal dumbbell ganglioneuroma in cervical spine( report of 1 case and review of literature)

作　　者：高方友[1] 李旭 蒋伟峰[1] 王曲[1] 刘窗溪[1] 韩国强[1] 曹颖[3] 

机构地区：[1]贵州省人民医院神经外科,贵阳550002 [2]贵阳市第三人民医院神经外科 [3]贵州省人民医院病理科,贵阳550002

出　　处：《临床神经外科杂志》2013年第5期263-265,共3页Journal of Clinical Neurosurgery

摘　　要：目的探讨颈段椎管内外哑铃形节细胞神经瘤的临床表现、诊断及治疗。方法报告1例颈段椎管内外哑铃形节细胞神经瘤,结合文献复习,回顾分析其临床表现、诊断及治疗。结果颈段椎管内外节细胞神经瘤影像学表现常为哑铃形,易误诊为神经鞘瘤;可直接起源于椎管内,也可经椎管外长入椎管内,这与脊髓及脊神经根症状出现的早晚有关;病理表现为肿瘤组织中散在分布分化成熟的神经节细胞;主要依靠显微外科手术治疗。结论颈段椎管内外哑铃形节细胞神经瘤易误诊为神经鞘瘤,主要依靠术后病理检查确诊,一期显微外科手术切除效果好。Objective To investigate the clinical manifestations,diagnosis and treatment of intraand extra-spinal dumbbell ganglioneuroma（ GN） in cervical spine. Methods The clinical manifestations,diagnosis and treatment of one patient with intra- and extra-spinal dumbbell GN in cervical spine were reported and analyzed retrospectively with review of the literature. Results The intra- and extra-spinal dumbbell GN was frequently misdiagnosed as schwannoma,the tumor could originate from the intra-spinal canal,but also extra-spinal canal,which decided that its clinical symptoms and signs occurred sooner or later,histopathology showed that mature ganglion cells scattered in tumor tissue,the tumor could be excised by microsurgery. Conclusions The dumbbell-shaped GN is frequently misdiagnosed as schwannoma,the diagnosis are usually comfirmed by the postoperative pathology. A good effect for intra-and extra-spinal dumbbell GN in cervical spine can be obtained by one-stage microsurgical excision.

关 键 词：颈椎 椎管内肿瘤 节细胞神经瘤 

分 类 号：R739.42[医药卫生—肿瘤]