荧光内镜在医疗诊断中的应用观察  

Clinical Observation of Fluorescence Endoscopy in Medical Diagnosis

作　　者：叶衍铭[1] 戈之铮[1] 萧树东[1] 龚帅[1] 郑家骠[1] 夏敬芳[1] 叶翔[1] 

机构地区：[1]上海交通大学医学院附属仁济医院荧光内镜课题组,上海市200127

出　　处：《中国医疗器械杂志》2013年第6期457-459,共3页Chinese Journal of Medical Instrumentation

基　　金：上海市重大/重点科技攻关课题(10441901700)

摘　　要：癌前病变和早期肿瘤因没有明显的形态特征,肉眼难于发现,常规诊断手段也不易识别。荧光内镜利用能精确反映组织内部微小变化的荧光技术,使这一状况产生突破性的改变。该课题组利用荧光内镜对200例消化道恶性肿瘤患者进行检测,初步得到总的诊断准确率、敏感性、特异性分别为94.0%、94.6%、93.5%的良好效果。由此可见,荧光内镜检查对消化道恶性肿瘤的诊断具有很高的敏感性,在病变形态特征不明显的情况下较普通内镜有更大的优势,易于发现肉眼难以识别的可疑病灶。并且可在图像指示下精确引导活检,对提高早期癌的检出率具有重要意义和广阔的发展前景。It＇s difficult to diagnose precancerous lesion and early cancer for a long time, because both of them haven＇t typical morphological characteristics. As a novel diagnostic modality, fluorescence endoscopy can accurately reflect minimal changes in human＇s tissue, thus making a meaningful progress for cancer diagnosing. 200 patients were examined by fluorescence endoscopy to evaluate the diagnostic value. The overall accuracy, sensitivity and specificity for detecting malignant gastrointestinal tumor was 94.0%, 94.6% and 93.5%, respectively. Thus, fluorescence endoscopy can be used to diagnose malignant gastrointestinal tumors with high white light endoscopy especially in detecting the atypica can also guide target biopsy, is significant to improve the validity and reliability, and is advantageous over conventional and suspicious lesions. Furthermore, fluorescence endoscopy early cancer detection rate, has a broad development prospect.

关 键 词：荧光内镜 消化道肿瘤 诊断 应用前景 

分 类 号：R735[医药卫生—肿瘤]