电镜下人胎盘滋养细胞的凋亡形态及其DNA缺口末端标记的对比研究  

COMPARATIVE INVESTIGATION ON APOPTOSIS OF PLACENTA TROPHOCYTE WITH EM AND DNA-NICK END ABELLING

作　　者：张瑞祥[1] 赵晓明[1] 金小平[1] 齐洁敏[1] 李玉红[1] 张玉娟[2] 胡建功[1] 

机构地区：[1]承德医学院超微病理研究室,河北承德067000 [2]承德医学院附属医院妇产科

出　　处：《承德医学院学报》2000年第4期118-121,共4页Journal of Chengde Medical University

摘　　要：目的 :本文提出胎盘滋养细胞结是 Keer描写的凋亡小体以外的另一种凋亡形态。方法 :用电镜系统地观察 :人胎盘滋养细胞生长、发育和衰老 ,并进一步用 DNA缺口标记做了对比观察。结果 :合体细胞结终末超微结构符合细胞凋亡形态特征。讨论 :胎盘滋养细胞凋亡从分子水平开始至超微结构及细胞形态变化是一个发展过程。Objective:The article sports that syntrophobleastic knots wee amother forms of appototic bodies who keer was elescriped.Methods:With electron microscopy,the growth develpoment and senility of placenta trophocyte was observed,systematically and comparative investigation.Was porfomed with DNA-nick and labelling technology.Results:Syntrophoblastic knots presented a coincidental ultrastructural characteristic with apoptosis.Conclusion:Apoptosis of placenta trophocyte was a develpoment process.From molecular level to ultrastructure and morphologic change of cells.

关 键 词：胎盘滋养细胞 凋亡 DNA缺口末端标记 电镜 

分 类 号：R361.3[医药卫生—病理学]