防癌筛查妇女中人乳头状瘤病毒感染状况分析  

An Analysis on HPV Infection Status in Screened Women

作　　者：魏葆珺[1] 李学祥[1] 齐军[1] 

机构地区：[1]中国医学科学院肿瘤医院肿瘤研究所,北京100021

出　　处：《中国肿瘤》2013年第11期885-887,共3页China Cancer

摘　　要：[目的]了解防癌筛查妇女中HPV感染状况及分布特点,为宫颈癌防治提供依据。[方法]采用HybriMax技术对5880例防癌筛查妇女进行HPV感染检测。[结果 ]5880例防癌筛查妇女中HPV阳性1105例,阳性率为18.80%,21种型别均被检测出。高危型以HPV16、HPV52和HPV58最常见,低危型最常见的为HPV53和HPVcp8304。阳性感染者中228例为多重感染,多重感染率为3.88%(228/5880),占阳性例数的20.63%,其中二重感染最多见。[结论]HPV亚型感染分布以HPV16、HPV52和HPV58为主,其分布与宫颈癌前病变及宫颈癌密切相关。[Purpose] To investigate the HPV infection status and age distribution in screened women,to provide basis for prevention and control of cervical cancer. [Methods] A total number of 5880cases were detected for HPV by HybriMax. [Results] The number of positive cases was 1105 out of5880. Positive rate of HPV infection was 18.80%. All the 21 genotypes of HPV were tested out. The most common high-risk genotype were HPV16,HPV52 and HPV58,whereas HPV16 and HPVcp8304 were the most common low-risk genotypes. The multiple infection rate was 3.88%（228/5880）. Double infection was common. [Conclusion] HPV16,HPV52 and HPV58 serves as the most common genotypes in HPV. The HPV distribution closely correlates to cervical precancerous lesions and cervical cancer.

关 键 词：人乳头状瘤病毒 导流杂交 筛查 宫颈癌 

分 类 号：R737.33[医药卫生—肿瘤]