我国真菌性角膜病高发区致病真菌种类调查  

Spectrum of mycotic keratitis in China

作　　者：王丽娅[1] 张月琴[1] 王刚生[2] 王印其[1] 王丽英[3] 田骋 高长凤[5] 

机构地区：[1]河南省眼科研究所,河南郑州450003 [2]河北医科大学二院,河北石家庄050012 [3]连云港市中医院,江苏连云港222026 [4]南阳卫校附院,河南南阳473056 [5]河南省眼科研究所河,南郑州450003

出　　处：《河南医学研究》2000年第4期357-359,共3页Henan Medical Research

基　　金：河南省自然科学基金资助课题。

摘　　要：目的：了解我国真菌性角膜病高发区的致病真菌种类以及致病菌种在各地区间的差异。方法：对我国华中的郑州地区、华北的石家庄地区以及华南的广州地区１９７５年１月至１９９７年６月间６１５例真菌性角膜炎患者的致病菌进行分析并分类到种。结果：６１５例菌分为１８属４７种。华北及华中地区的主要致病菌属基本相同，依次为镰孢菌属、曲霉属、青霉属，但主要致病菌种两地区略有差异。广州地区１９７５年１月至１９８６年１２月的资料显示主要致病菌依次为曲霉属、镰孢菌属、青霉属，近８年则依次为镰抱菌属、曲霉属、弯孢霉属。结论：我国真菌性角膜炎的首位致病菌为镰抱菌属。Objective: To investigate the spectrum of mycotic keratitis in China. Methods: We scraped and evaluated 615 mycotic keratitis in the microbiology laboratory of Zhengzhou(Huazhong areas), Shijiazhuang(Huabei areas) and Guangzhou (Huanan areas) during the twenty - two yares between Jan. 1, 1975 and Jun. 30, 1997. Results:Organisms of 18 genus and 615 species isolated from corneal ulcers were shown in Table 2, 3. Fusarium species were the most frequent isolated(65%, 33 .3% and 39.2% )in Zhengzhou, Shijiazhuang and Guangzhou, followed by Aspergillus(20. 5% in Zhengzhou, 21 .7% in Shijiazhuang, 30.7% in Guangzhou), Penicillium (3 .6% in Zhengzhou, 11 .6% in Shijiazhuang)and Curvularia (13.1% in Guanzhou). Between Jan. 1, 1975 and Dec. 31, 1986, Aspergillus species were most commonly isolated in guangzhou (48.5%), followed by Fusarium (27. 1% ) and Penicilliun(14. 2% ). Conclusion: Just as different regions of the world are characterized by specific endemic infections, the predominating organisms in comeal fungal infections the also vary throughout the world. These regional differences in causative organisms in mycotic keratitis are clinically important because they influence the initial and more definite therapy. This study showed that Fusariums spotes were the most common organisms of mycotic keratitis in China.

关 键 词：眼感染 真菌性 角膜 中国 

分 类 号：R772.2[医药卫生—眼科]