恒牙胚对机械损伤耐受性的实验研究  

Experimental study on the resistance of tooth germs to mechanical trauma

作　　者：赵继刚[1] 古向生[2] 

机构地区：[1]南方医科大学附属南海医院,佛山528200 [2]中山大学光华口腔医学院附属口腔医院

出　　处：《实用口腔医学杂志》2013年第6期788-790,共3页Journal of Practical Stomatology

摘　　要：目的:观察手术损伤对牙胚生长发育的影响。方法:选用12只幼犬的48颗尖牙胚随机分为6组。对照组:对牙胚不进行损伤;实验组1:仅暴露牙胚;实验2、3、4组:暴露牙胚后分别给予3、6、9 kg/25 mm2挤压力;实验组5在开窗后刮除暴露的牙囊。8周后处死动物,观察受试牙齿生长发育情况;测量其冠根长度,计算冠根长度均数和HE染色镜检。结果:对照组与实验1、2组均无明显异常,测量指标差异无显著性(P>0.05);实验3、4、5组冠根长度较对照组短(P<0.05);实验组4与实验组5分别有2例和3例牙髓坏死,牙体呈灰褐色。结论:显露牙囊和轻度挤压不会对其发育造成明显影响,但当损伤超过一定限度,损伤是不可逆的。Objective：To observe the effects of surgical trauma on the development of teeth germs.Methods：48 canine germs of 12 dogs aged 8-12 weeks were divided into 6 groups randomly.The teeth germs in control group were not treated.those in group 1 were only exposed,in group 2,3,4 were given 3 kg/25 mm2,6 kg/25 mm2 and 9 kg/25 mm2 pressure respectively after bone removal.8 weeks later,the dogs were killed and the teeth were extracted,observed,measured and histologically examined.Results：There was no significant difference about teeth form and measurement items between control group and experimental group 1 or group 2 （P ＞ 0.05） ;the roots in the experimental group 3,4 and 5 were shorter than those in the control group （P ＜ 0.05）.The pulp of 2 teeth in group 4 and that of 3 teeth in group 5 was necrotic and the teeth were grey.Conclusion：Exposing dental sac and light pressure can not affect the development of tooth germs.But,heavy pressure may result in irreversal damage and impair the development of the germs.

关 键 词：牙胚 机械损伤 耐受性 

分 类 号：R782.1[医药卫生—口腔医学]