卵巢恶性畸胎瘤临床及预后分析  

Analysis of Clinical and Prognosis of Malignant Ovarian Teratoma

作　　者：余江涛[1] 郑飞云[1] 陈志文[1] 

机构地区：[1]温州医学院附属第一医院妇科,325000

出　　处：《医学研究杂志》2013年第11期98-101,共4页Journal of Medical Research

摘　　要：目的探讨卵巢恶性畸胎瘤的临床、病理特点及相关预后因素。方法回顾性分析笔者医院2000年6月～2009年5月收治的16例卵巢恶性畸胎瘤患者的临床病理资料，并结合相关文献进行分析。结果16例患者中有9例为卵巢畸胎瘤鳞癌变，患者平均年龄57．3±6．2岁，5例患者为未成熟畸胎瘤，平均年龄29．2±19．5岁，各有l例患者为未成熟畸胎瘤伴类癌及卵巢成熟性畸胎瘤伴灶区类癌。单因素和多因素生存分析结果显示，手术病理分期及组织学类型是影响患者总的幸存率的相关因素。结论卵巢恶性畸胎瘤手术病理分期越晚，分化程度越低，患者生存率越低，治疗遵循以手术为主、化疗为辅的原则。Objective To explore the clinical, pathological features and prognostic factors of ovarian malignant teratoma. Methods There was a retrospective analysis about 16 patients of ovarian malignant teratoma from June 2000 to May 2009, while clinic and pathologi- cal factors and prognostic factors were analyzed. Results In 16 patients, there are 9 patients of teratoma of ovary squamous （：ell carcino- ma of variable with average age of 57.3 ± 6.2 years old. 5 patients of ovarian immature teratoma＇ s average age is 29.2 ± 19.5 years o[d. Each have one patients with immature teratoma of ovary with carcinoid and mature tcratoma of ovary with focal area of carcinoid. Survival analysis of single factor and muhifaetor showed that pathological stage of operation and histological type are factors affecting overall survival rate for patients with the ovarian malignant teratoma. Coelusiou The patients of ovarian malignant teratoma with the later pathological stage of operation and low differentiation had lower survival rates. The treatment is the main therapeutic principles of operation, and chem- otherapy supplemented.

关 键 词：卵巢恶性畸胎瘤 预后 治疗 

分 类 号：R737.31[医药卫生—肿瘤]