功能区胶质瘤手术的基本策略与方法  

Basic strategies and methods of neurosurgery on glioma in danger functional area

作　　者：漆松涛[1] 李志勇[1] 方陆雄[1] 潘军[1] 欧阳辉[1] 彭林[1] 李伟光[1] 

机构地区：[1]南方医科大学南方医院神经外科,广州510515

出　　处：《中华神经外科杂志》2013年第11期1083-1086,共4页Chinese Journal of Neurosurgery

基　　金：国家自然科学基金青年科学基金资助项目（81101921）

摘　　要：目的总结危险功能区胶质瘤手术的基本策略和操作方法。方法回顾性分析67例大脑危险功能区胶质瘤手术的临床资料。结果31例丘脑胶质瘤、20例脑干胶质瘤、9例松果体区胶质瘤和7例鞍区胶质瘤中，切除肿瘤的手术操作时间平均为1．16h，术后复查MRIT1加权增强扫描显示全切除61例（91％），次全切除6例（9％），术后平均KPS评分大于70分，所有患者均未出现新增的永久性神经功能障碍。结论在危险功能区胶质瘤手术中遵循“雕刻式”手术策略和膜性结构理念，可以达到最大范围安全切除肿瘤，获得良好手术效果。Objective To summarize the basic strategies and methods of neurosurgery on glioma in danger functional area. Methods The clinical data of 67 cases of brain glioma surgery in danger functionl area was retrospective analyzed. Results Which of 31 patients with thalamic glioma, 20 cases of brain stem glioma, 9 cases of gliomas in pineal region and 7 cases of glioma in saddle area were reviewd. The surgery time of resection the tumor is averaged 1.16 hours. Total resection through postoperative review MRI T1 - weighted enhancement scanning is showed in 61 cases （91%） , subtotal resection in 6 cases （9%）, postoperative review in postoperative KPS score is greater than an average of 70 points, all the patients were not present new permanent nerve dysfunction. Conclusions Following ＂topographic anatomy＂ operation concept, strategy and membranous structure in the functional area, glioma surgery could achieve maximum safe removal of the tumor, and obtain good operation effect.

关 键 词：功能区 神经胶质瘤 显微神经外科 

分 类 号：R739.4[医药卫生—肿瘤]