别克参提取物抗氧化活性研究  

Study on Antioxidant Activity of Erythronium sibiricum Extract

作　　者：陈春丽[1] 田兰[1] 勉强辉[1] 穆沙.艾力 热娜.卡斯木[1] 

机构地区：[1]新疆医科大学药学院,乌鲁木齐830011

出　　处：《中国药房》2013年第47期4425-4428,共4页China Pharmacy

基　　金：新疆维吾尔自治区研究生科研创新项目(No.XJGRI2013077);新疆医科大学科研创新基金项目(No.XJC2011116)

摘　　要：目的:研究别克参提取物的体外抗氧化活性。方法:采用清除二苯代苦味酰基(DPPH)自由基、2,2′-氨基(-3-乙基-苯并噻唑啉-6-磺酸)二氨盐(ABTS)自由基与超氧阴离子(O2-)自由基法,对别克参不同提取物的体外抗氧化活性进行评价。结果:别克参不同提取物清除DPPH·自由基、ABTS·自由基的能力强弱顺序为:乙酸乙酯提取物>石油醚提取物>正丁醇提取物>水提取物。别克参不同提取物对O2-自由基有一定的清除能力,但不明显。结论:别克参不同提取物抗氧化活性差异可能与各部位中所含抗氧化成分的种类和结构有关。OBJECTIVE： To investigate antioxidant activity of Erythronium sibiricum extracts in vitro. METHODS： The antioxidant activities of different E. sibiricum extracts were evaluated in vitro using scavenging DPPH. free radical, scavenging ABTS. free radical and scavenging superoxide anion radical. RESULTS： Different E. sibiricum extracts had obvious scavenging capacity to DPPH. free radical and ABTS. free radical in descending order： ethyl acetate extract〉petroleum ether extract〉n-butanol extract〉 water extract. Different E. sibiricum extracts showed scavenging capacity to O2- radical but was not very strong. CONCLUSIONS： Different extracts of E. sibiricum exhibit different antioxidant activities, which may be associated with the types and structures of antioxidant components.

关 键 词：别克参 极性部位 自由基 抗氧化活性 

分 类 号：R285[医药卫生—中药学] R932[医药卫生—中医学]