超声波辅助制备牛磺酸的研究  

Synthesis of taurine with ultrasonic assisted method

作　　者：黄明星[1] 周彩荣[1] 黄翠[1] 

机构地区：[1]郑州大学化工与能源学院,河南郑州450001

出　　处：《现代化工》2013年第11期50-53,共4页Modern Chemical Industry

摘　　要：对乙醇胺酯化法合成牛磺酸工艺中的磺化反应进行了研究,以亚硫酸铵作磺化剂,超声波辅助加热控制反应温度,分别采用单因素试验法和正交试验设计法对磺化反应进行优化。磺化反应的最佳工艺条件为:反应温度为75℃,反应时间为12h,物料配比(n(NH4)2SO3∶n酯)为1.65,酯的加料方式为4次,在此条件下2-氨基乙醇硫酸酯的转化率达到65.30%。The sulphonating reaction of preparation of taurine with ultrasonic assisted method is studied. Both the single factor experiment design and the orthogonal experimental design method are used to optimize the sulphonating reaction using ammonium sulfite as sulfonating agent and ultrasonic auxiliary heating to control the reaction temperature. The conversion of 2-aminoethanol sulfate can reach 65.30% under the following conditions：75~C of temperature, 12 hours of reaction time, 1.65 of the mole ratio of ammonium sulfite to 2-aminoethanol sulfate and 4 times of adding 2- amino ethanol sulfate.

关 键 词：牛磺酸 亚硫酸铵 超声波 磺化反应 

分 类 号：TQ031.2[化学工程]