气相色谱-质谱法测定化妆品中16种有机氯农药  

Simultaneous determination of 16 organochlorine pesticides in cosmetics by gas chromatographymass spectrometry

作　　者：周相娟[1] 赵玉琪[1] 许华[1] 

机构地区：[1]北京市海淀区产品质量监督检验所,北京100094

出　　处：《分析试验室》2013年第12期74-78,共5页Chinese Journal of Analysis Laboratory

基　　金：国家质量监督检验总局科技计划项目(2011QK045)资助

摘　　要：建立了气相色谱．质谱（GC／MS）测定化妆品中16种有机氯农药的分析方法。化妆品经酸性乙腈提取、凝胶色谱（GPC）净化后进行GC／MS测定，外标法定量。结果表明所有农药在0．01～1mg／L范围内线性关系良好。方法的检出限为O．01～0．1mg／kg。在0．3mg／kg的添加水平下，化妆水、乳液和唇膏3种基质中16种有机氯农药的平均加标回收率为71．6％～129％，相对标准偏差（RSD）为1．2％～6．6％，该方法适用于化妆品中16种有机氯农药的同时测定，可为我国建立化妆品中相应检测方法提供参考。A gas chromatography-mass spectrometric method was developed for the determination of 16 organoehlorine pesticides in cosmetics. This method includes simple extraction of the samples with acetonitrile containing 1% acetic acid followed by gel permeation chromatography （GPC） for cleanup step and GC-MS for detection. The method had a good linear relationship in the range of 0. 01 - 1.00 mg/L and the limits of detection ranged from 0. 01 to 0. 1 mg/kg. The average recoveries of 16 organochlorine pesticides were in the range from 71.6% to 129% at the spiked level of 0. 3 mg/kg into three cosmetic matrixes （Toner, lotion, lipstick） with the relative standard deviations （RSDs） of 1.2% - 6. 6%. The recommended method is simple, rapid, sensitive and specific. It is reliable for the routine monitoring of 16 organochlorine pesticide in cosmetics.

关 键 词：有机氯农药 化妆品 凝胶色谱 气相色谱-质谱法 

分 类 号：O657.63[理学—分析化学]