肝恶性肿瘤行规则性肝切除术与不规则肝切除术的相关因素比较  

Regular versus irregular liver resection for malignant tumors of the liver

作　　者：寇昌华[1,2] 钱海鑫[1] 赵子明[3] 

机构地区：[1]苏州大学附属第一医院,江苏省苏州市215006 [2]徐州市中心医院肿瘤外科,江苏省徐州市221009 [3]徐州医学院药学院,江苏省徐州市221000

出　　处：《世界华人消化杂志》2013年第32期3566-3570,共5页World Chinese Journal of Digestology

基　　金：国家自然科学基金资助项目;No.81102381~~

摘　　要：目的:探究肝恶性肿瘤两种肝切除手术方式的围手术期相关因素,比较二者的临床应用优越性,从而为以后的治疗提高参考依据.方法:采取回顾性方法对我院2010-01/2012-12之间收录的120例肝恶性肿瘤肝切除手术患者的临床资料进行分析.结果:手术方式与围手术期多因素分析,两组的出血量、并发症发生率和死亡率以及住院时间比较无明显的差异(P>0.05),无统计学意义.非规则性肝切除术与规则性肝切除术手术手术时间分别为211.3 min±102.6 min、221.8min±101.7 min,规则性肝切除组中手术时间明显地高于非规则性肝切除组中手术时间,数据的比较具有明显的差异(P<0.05).结论:规则性肝切除的美学效果明显的优于非规则性肝切除的效果,但是对于肿瘤较小的患者,实施非规则性肝切除治疗更加简单有效,并且达到根治的效果,对于多数伴肝硬化的患者采取规则性肝切除的安全性更高.临床中应有效地掌握患者的病情状况,从而正确的采取非规则性肝切除和规则性肝切除治疗,提高安全性.AIM： To compare the clinical effects of regular versus irregular liver resection for malignant tu- mors of the liver. METHODS： Clinical data for 120 patients who underwent liver resection for malignant tumors of the liver at our hospital from January 2010 to December 2012 were analyzed retrospectively. RESULTS： The amount of bleeding, the inci- dence of complications and mortality, and thelength of hospital stay showed no significant differences （all P 〉 0.05） between patients un- dergoing irregular liver resection and those un- dergoing regular liver resection. The operative time was significantly longer in the regular liver resection group than in the irregular liver resec- tion group （221.8 min ±101.7 min vs 211.3 min ±102.6 rain, P 〈 0.05）. CONCLUSION： The aesthetic effect of regular liver resection is better than that of irregular liver resection. For patients with small tumors, irregular liver resection is more simple and ef- fective and can achieve radical results. For those patients with cirrhosis, regular liver resection has higher safety. Liver resection strategy should be selected based on the patient＇s condition to improve effectiveness and safety.

关 键 词：肝脏恶性肿瘤 不同术式 肝切除术 相关因素 

分 类 号：R735.7[医药卫生—肿瘤]