化疗联合放疗对局限期小细胞肺癌放疗的时机选择  

作　　者：吴小进[1] 米燕燕[2] 桑纯利[1] 王伟[1] 殷咏梅[3] 张庆国[1] 

机构地区：[1]江苏省徐州市第一人民医院,221002 [2]徐州医学院,221004 [3]江苏省人民医院,210029

出　　处：《浙江临床医学》2013年第12期1777-1779,共3页Zhejiang Clinical Medical Journal

基　　金：国家自然科学基金资助（编号：BA11-81172503）

摘　　要：目的：探讨放疗联合化疗对局限期小细胞肺癌时放疗的时机选择。方法将将72例局限期小细胞肺癌患者随机分为A、B、C、D四组，各18例，分别于化疗1个周期、2个周期、3个周期后及化疗结束后进行放疗，观察各组的疗效及不良反应。结果 A组治疗效果最佳，但不良反应剧烈，D组不良反应最低，但治疗效果不及其他三组，C组在获得良好治疗效果的同时不良反应患者能够耐受。结论治疗局限期小细胞肺癌化疗3个周期后进行放疗时机最佳。Objective To find the optimal timing to add the radiotherapy in the treatment for limited-stage small cell lung cancer. Methods Divided the patients into four groups（A、B、C and D）,all of the patients received the chemotherapy first,than had the radiotherapy in the treatment after the first cycle（Group A）、the second cycle（Group B）、the third cycle （Group C）and the fourth cycle（Group D）respectively.The efficacy were observed after the treatment of the two groups as well as the occurrence of adverse reactions. Results The Group A had the best efficay,but at the same time the adverse reactions were severe;Group D had the lowest strength of the adverse reactions,but the efficacy was not as good as another groups;Group C had a low strength of the adverse reactions as well as the good efficacy. Conclusion The optimal timing to add the radiotherapy in the treament for limited-stage small cell lung cancer is after the moment of the third cycle of the chemotherapy.

关 键 词：局限期小细胞肺癌 放疗 时机选择 

分 类 号：R734.2[医药卫生—肿瘤]