艾滋病合并巨细胞病毒性视网膜炎的临床研究  

Clinical Research on AIDS Patients Complicated with Cytomegalovirus Retinitis

作　　者：蒋瑶祁[1] 徐宁[1] 王晓黎[1] 叶楠[1] 袁超[1] 

机构地区：[1]广东省广州市第八人民医院眼科,广东广州510440

出　　处：《临床医学工程》2013年第12期1496-1497,共2页Clinical Medicine & Engineering

基　　金：广州市医药卫生科技项目(20131A011074)

摘　　要：目的探讨艾滋病合并巨细胞病毒性视网膜炎的病变特点、诊断方法及治疗原则。方法对38例（60眼）AIDS合并CMVR患者的临床资料进行回顾性分析，包括诊断标准、临床表现、治疗方法及疗效。结果发病1周内、1～2周、2～4周、〉4周患者的治疗有效率分别为100％、94．4％、76．9％、64．o％，不同发病时间的治疗有效率相比较，差异有统计学意义（P〈0．05）。结论早期诊断并采取有效抗病毒治疗措施，有助于防止AIDS合并CMVR导致的不可逆性视力障碍及其他眼部并发症。Objective To explore the lesion features, diagnostic methods and treatment principles of AIDS patients combined with cytomegalovims retinitis （CMVR）. Methods The clinical data of 38 cases （60 eyes） of AIDS patients combined with CMVR were retrospectively analyzed, including diagnostic criteria, clinical manifestations, treatment methods and efficacy. Results The treatment efficiency at patients getting disease within 1 week, 1 to 2 weeks, 2 to 4 weeks, 〉 4 weeks was 100%, 94.4%, 76.9%, 64.0%, respectively. The treatment efficiency at different onset time was significantly different, with statistical significance （P 〈0.05）. Conclusions Early diagnosis and effective anti-viral treatment will help prevent irreversible visual disturbance and other ocular complications for AIDS patients combined with CMVR.

关 键 词：艾滋病 巨细胞病毒性视网膜炎 更昔洛韦 

分 类 号：R774.11[医药卫生—眼科] R512.91[医药卫生—临床医学]