NBI在判断幽门螺杆菌相关性胃炎中的作用  

Effect of NBI on diagnosis of Hp associated gastritis

作　　者：周晓永[1] 李亚其[1] 李修岭[1] 杨玉秀[1] 王修齐[1] 杨惠[1] 

机构地区：[1]河南省人民医院消化内科,郑州450003

出　　处：《中国实用医刊》2013年第24期48-49,共2页Chinese Journal of Practical Medicine

摘　　要：目的 研究在放大内镜下应用窄带成像（NBI）技术观察幽门螺杆菌（Hp）感染时胃体黏膜微细结构变化的特征,进而探讨NBI在判断Hp相关性胃炎中的作用.方法 在放大内镜下应用NBI对180例有不同上消化道症状患者的胃体黏膜微细结构进行观察和分型,用胃黏膜组织学检查（生物电荷法）和13C呼气试验检测Hp感染,分析胃体黏膜微细结构与Hp之间的联系.结果 180例患者中Hp感染阳性72例,Hp感染阴性108例,胃体下部大弯侧集合静脉分为规则型（R）、不规则型（Ⅰ）、消失型（D）,Hp感染率分别为6.5％、65.2％和81.5％,其中D及Ⅰ型感染率明显高于R型,且差异有统计学意义（P＜0.05）.结论 在放大内镜及NBI下Hp感染时胃体黏膜微细结构特点是集合静脉不规则、紊乱、模糊、甚至消失,且图像清晰度显著优于单独应用放大内镜.Objective To study the microstructural features of gastric mucosa infecting with He licobacter pylori （Hp） by magnifying endoscopy with narrow-band imaging（NBI）,then to study the effect NBI on Hp assciated gastritis.Methods Microstructures of gastric mucosa in 180 patients with dyspepsia were observed and classified by magnifying endoscopy with narrow-band imaging.Biological charge method and the breath test of 13C were used to detect the Hp infection.The relationship between microstructures of gastric mucosa and Hp infection was analyzed.Results Of the 180 patients,Hppositive in 72 cases,and negative in 108 cases.The morphology of lower and greater curvature part of gastric corpus collecting venules was subdivided into type R（regular）,type Ⅰ（irregular） and type D（disappeared）,correspondent Hp infection rates were 6.5％,65.2％ and 81.5％.The rate of Hp infection in type D and type Ⅰ was significantly higher than that in type R （P ＜ 0.05）.Conclusions Under magnifying endoscopy with narrow-band imaging,Hp positive gastric mucosal microstructure shows the features of irregular,confused,obscured or disappeared collecting venules in corpus.The image clarity is significantly better than that of single application of magnifying endoscopy.

关 键 词：放大内镜 窄带成像 幽门螺杆菌 集合静脉 

分 类 号：R573.3[医药卫生—消化系统]