脐尿管癌临床特点及治疗体会(附6例报告)  

Clinical features and treatment experience of urachal carcinoma(Report of 6 cases)

作　　者：李凡[1,2] 杨丽丽[3] 刘述成[1] 张龙[1] 石瑛[1] 杨雄[1] 李兵[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院泌尿外科,武汉430022 [2]武汉市中心医院泌尿外科,武汉430014 [3]华中科技大学同济医学院附属同济医院病理研究所

出　　处：《临床泌尿外科杂志》2013年第12期923-925,共3页Journal of Clinical Urology

摘　　要：目的：探讨脐尿管癌的临床特点，增加对脐尿管癌的了解，提高诊治水平。方法：回顾性分析收治的6例脐尿管癌患者的临床资料：6例患者中，1例行膀胱部分切除术，2例行根治性全膀胱切除术，3例行扩大性膀胱部分切除术。结果：术后随访6个月～3年，1例行膀胱部分切除术患者术后7个月原位复发．再行根治性全膀胱切除术，术后辅以全身化疗。1例行根治性全膀胱切除术患者术后13个月死亡。3例行扩大性膀胱部分切除术患者中，1例术后9个月复发，并与6个月后死亡，其余2例分别随访6个月、18个月未见复发及转移。结论：脐尿管癌是一种少见的膀胱恶性肿瘤，预后差。影像学检查及膀胱镜检查的综合应用是诊断脐尿管癌的主要方法。手术治疗是脐尿管癌的主要治疗方法，扩大性膀胱部分切除术是值得推荐的手术方式。Objective：To study the clinical features of urachal carcinoma so as to improve the understanding,diagnosis and treatment of this disease. Method： A retrospective study was done in six cases of urachal carcinama. One of them received conventional partial cystectomy. Two of them underwent radical cystectomy, while extensive partial eystectomy were performed in three of them. Result： The follow up period was from six months to three years. I.ocal recurrence appeared in one patient seven months after the conventional partial cystectomy, so we per- formed radical cystectomy combined with systemic chemotherapy. One patient received radical cystectomy died from extensive metastasis 13 months later. Among the three cases treated by extensive partial cystectomy, one case died 15 months postoperatively, other two cases had been alive without recurrence and metastasis up to the last follow-up period （18 months）. Conclusion：Urachal carcinoma is a rare bladder malignancy with poor progno- sis. The combined use of imaging examination and cystoscopy is the main method to diagnose the disease. Surgical excision is the main method of treatment and extensive partial cystectomy is recommended for urachal carcinoma.

关 键 词：脐尿管癌 诊断 治疗 

分 类 号：R737.14[医药卫生—肿瘤]