海德堡激光眼底扫描仪对POAG患者视盘结构的研究分析  

Analysis of optic disk structure tested by Heidelberg retinal tomography Ⅲ in patients with primary open angle glaucoma

作　　者：梁思颖[1] 黄丽娜[1] 樊宁[1] 申晓丽[1] 

机构地区：[1]暨南大学附属深圳眼科医院,中国广东省深圳市518020

出　　处：《国际眼科杂志》2013年第12期2471-2474,共4页International Eye Science

摘　　要：目的:评价海德堡激光眼底扫描仪(HRT-Ⅲ)对原发性开角型青光眼(primary open angle glaucoma,POAG)不同发展阶段的诊断能力。方法:采用海德堡激光眼底扫描仪对POAG患者65例116眼和正常人60例114眼进行视盘断层扫描获取视盘结构各参数;将正常人和POAG患者以及各期POAG患者的视盘参数进行对比分析;将POAG患者的视盘结构参数与视野平均缺损值进行相关分析。结果:POAG患者与正常人的视杯面积、盘沿面积、视杯容积、盘沿容积、杯盘面积比、盘沿视盘面积比、线性杯盘比、平均视杯深度、最大视杯深度、平均RNFL厚度的差异有统计学意义。早期、进展期、晚期POAG患者的视杯面积、盘沿面积、视杯容积、盘沿容积、杯盘面积比、盘沿视盘面积比、线性杯盘比、平均视杯深度、平均视网膜神经纤维层(retinal nerve fiber layer,RNFL)厚度的差异有统计学意义。POAG患者的视杯面积、视杯容积、杯盘面积比、线性杯盘比、平均视杯深度与视野平均缺损值呈正相关,而盘沿面积、盘沿容积、盘沿视盘面积比、平均RNFL厚度则与视野平均缺损值呈负相关。结论:HRTⅢ能够有效地反映POAG各阶段的视盘改变,与视野相关性好,为POAG的诊断提供了依据。AIM：To evaluate the diagnostic capability of Heidelberg retinal tomography-Ⅲ （ HRT-Ⅲ） for primary openangle glaucoma （ POAG） at different stages. METHODS： Sixty-five patients （ 116 eyes ） with POAG and 60 normal persons （114 eyes） were tested by HRT-Ⅲwith optic disk tomography to observe their optic disk structure parameters. The optic disk parameters of normal persons, patients with POAG, and patients of POAG at different stages were compared and analyzed. The correlation between optic disk parameters and mean defect of the visual field of patients were analyzed. RESULTS： There were statistical differences in cup area, rim area, cup volume, rim volume, cup/disk area ratio, rim/disk area ratio, linear cup/disk ratio, mean cup depth, maximun cup depth, mean retinal nerve fiber layer （ RNFL） thickness between normal persons and patients and among patients of the three stages （ early, developing and late）.A positive correlation was found between cup area, cup volume, cup/disk area ratio, linear cup/disk ratio, mean cup depth and mean defect of the visual field in POAG patients, while, a negative correlation was found between rim area, rim volume, rim/disk area ratio, mean RNFL thickness and mean deviation in POAG patients. CONCLUSION：HRT-Ⅲcan effectively reflect changes of optic disc in each stage of POAG. It shows a good correlation with visual field and provides basis for the diagnosis of POAG.

关 键 词：海德堡激光眼底扫描仪 原发开角型青光眼 视盘 

分 类 号：R775[医药卫生—眼科]