伴自发性消退的儿童腹膜后神经母细胞瘤1例报道并文献复习  

One case report of baby retroperitoneal neuroblastoma with spontaneous recession and literature review

作　　者：杨艳丽[1] 刘斌[1] 苏勤军[1] 史敏[1] 董亮[1] 

机构地区：[1]解放军兰州军区兰州总医院病理科,甘肃兰州730050

出　　处：《现代肿瘤医学》2013年第12期2825-2827,共3页Journal of Modern Oncology

摘　　要：目的:探讨婴儿神经母细胞瘤(nenroblastoma,NB)的临床病理及免疫组化特征。方法:分析1例伴自发性消退的儿童腹膜后NB,并复习近15年国内外有关文献报道,分析NB的临床、组织学及预后特点。结果:近15年我院病理科共收集NB 40例,其中仅见1例伴自发性消退的NB,国内外相关报道极其少见。瘤细胞Vimentin、NSE和S-100呈阳性表达。结论:NB好发于腹膜后、后纵隔的交感神经节,病理组织形态要与小圆细胞肿瘤相鉴别。免疫组化在NB的诊断和鉴别诊断中具有重要意义,发病年龄与预后密切相关。Objective ：To discuss the clinical pathology and immunohistochemical features of baby neuroblastoma. Methods： To analyse one case of baby retroperitoneal neuroblastoma with spontaneous and recession, and review relat- ed literature in recent 15 years. And prognosis features of neuroblastoma. Results： Reviewing the cases of our hospital pathology department in 15 years, there were 40 cases of neuroblastoma, with only one case NB accompanying with spontaneous recession. Referring literatures both home and abroad in 15 years, there were two reports about NB with spontaneous recession. Immune histochemical stain ： Vimentin, NSE, S - 100 were positive expressed. Conclusion： NB mostly develops in retroperitoneal and posterior mediastinum sympathetic ganglion and its pathomorphology should be differentiated with that of small round cell tumors. Immunohistochemistry plays an important role in the diagnosis and differential diagnosis of NB while the age of onset is closely related to prognosis.

关 键 词：神经母细胞瘤 自发性消退 免疫组化 预后 

分 类 号：R739.43[医药卫生—肿瘤]