沙利度胺对卵巢癌的化疗前景  

Effect prospect of thalidomide in ovarian cancer chemotherapy

作　　者：杜娟[1] 

机构地区：[1]昆明市妇幼保健院妇二科腔镜中心,云南昆明650000

出　　处：《现代肿瘤医学》2013年第12期2850-2853,共4页Journal of Modern Oncology

基　　金：云南省教育厅资助课题项目(编号:08c0103)

摘　　要：沙利度胺早期曾作为治疗早孕反应的镇静止吐药而广泛被使用,但因其有很强的致畸作用于1963年被停止应用。近年来研究表明,沙利度胺具有免疫调节和抗血管生成作用。对多发性骨髓瘤、急性髓系白血病、子宫肿瘤、前列腺癌等均有一定的疗效,而对其它肿瘤的作用也在进一步研究中。本文对沙利度胺治疗卵巢癌的研究进展做一综述。Thalidomide as a treatment for early pregnancy has antiemetic and sedative response is widely used, but because there was a strong teratogenic effect in 1963 stopped the application. Recent studies have shown that thalido- mide has a role in immune regulation and anti - angiogenesis. For multiple myeloma, acute myeloid leukemia, uterine cancer, prostate cancer, and so have a certain effect, but also the role of other tumors. In this paper, the effect of tha- lidomide on ovarian cancer was reviewed.

关 键 词：沙利度胺 卵巢癌 治疗 

分 类 号：R737.31[医药卫生—肿瘤]