脑出血患者T淋巴细胞亚群的变化  

Changes of T lymphocyte subsets in patients with cerebral hemorrhage

作　　者：张斌[1] 

机构地区：[1]金坛市人民医院神经外科,江苏省213200

出　　处：《江苏医药》2013年第23期2858-2859,共2页Jiangsu Medical Journal

摘　　要：目的探讨脑出血患者T淋巴细胞亚群的变化。方法 36例脑出血患者为脑出血组,检测病情轻重不同时血T淋巴细胞亚群数量。健康体检者30名为对照组。结果脑出血组急性期CD3+、CD4+数量和CD4+/CD8+比值均明显低于恢复期和对照组(P<0.05)。脑出血量大、病情重患者的CD3+、CD4+数量和CD4+/CD8+比值均明显低于出血量少、病情轻者(P<0.05)。结论脑出血患者急性期存在T淋巴细胞免疫功能低下;出血量越大和病情越重的患者,免疫功能越为低下。Objective To exlplore the changes of T lymphocyte subsets in patients with cerebral hemorrhage. Methods The amounts of T lymphocyte subsets were measured in 36 patients with cerebral hemorrhage in defferent phases and bleeding volumes and 30 healthy control people. Results The amounts of CD3＋, CD4＋ and CD4＋/CD8＋ ratio were lower in cerebral hemorrhage patients in acute phase than those in recovery phase and in healthy controls（P〈0. 05）,which were lower in cerebral hemorrhage patients with large amount bleeding and severe condition than those with less bleeding and slighter condition（P^0. 05）. Conclusion The immune function of T lymphocytes is decreased in cerebral hemorrhage patients in acute phase, which is lower in those with large amount of bleeding and severe condition than those with less bleeding and slighter condition.

关 键 词：脑出血 T淋巴细胞亚群 免疫功能 

分 类 号：R743[医药卫生—神经病学与精神病学]