水灌肠^(18)F-FDGPET/CT鉴别诊断良恶性结直肠病变  

Water enema ^(18)F-FDG PET/CT in differential diagnosis of malignant and benign lesions in rectum and sigmoid colon lesions

作　　者：张占文[1] 陈斐妮[1] 吕清湖 张杰[1] 卢丹[1] 胡平[1] 

机构地区：[1]中山大学附属第六医院影像检验中心,广东广州510610

出　　处：《中国医学影像技术》2013年第12期2002-2006,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨水灌肠PET/CT鉴别结直肠良恶性病变的价值。方法对常规PET/CT检查发现的45例直肠及乙状结肠局灶性或弥漫性FDG浓聚患者行水灌肠PET/CT显像,与肠镜或术后病理结果进行对照。结果水灌肠PET/CT扫描后诊断生理性摄取准确率为100%(15/15);诊断恶性肿瘤的敏感度为100%(18/18),特异度为92.59%(25/27),准确率为95.56%(43/45),阳性预测值为90.00%(18/20),阴性预测值为100%(27/27)。结论水灌肠PET/CT可有效排除结直肠生理性摄取18F-FDG,准确鉴别常规PET/CT难以诊断的良恶性结直肠病变。Objective To assess the feasibility of water enema 18F-FDG PET/CT in differential diagnosis of malignant and benign lesions in rectum and sigmoid colon. Methods Totally 45 patients with locally hypermetabolic lesions found by 18F-fluorodexyglucose （FDG） PET/CT in rectum and sigmoid colon underwent water enema 18F-FDG PET/CT. The results of water enema 18F-FDG PET/CT were compared with colonoscopy and surgical pathological examination. Results The diagnostic accuracy of water enema 18F-FDG PET/CT for physiological 18F-FDG uptake was 100% （15/15）. The diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value of water enema 18F-FDG PET/CT for malignant lesions was 100%（18/18）, 92.59% （25/27）, 95.56% （43/45）, 90.00% （18/20） and 100% （27/27）, respectively. Conclusion Enema water 18F-FDG PET/CT can effectively remove physiological uptake in colorectum and differ malignant and benign lesions of rectum and sigmoid colon that hard to be diagnosed with routine PET/CT.

关 键 词：直肠 乙状结肠 灌肠 正电子发射型体层摄影术 体层摄影术 X线计算机 18F 氟脱氧葡萄糖 

分 类 号：R574[医药卫生—消化系统] R445.6[医药卫生—内科学]