利培酮对痴呆患者精神病性等症状的疗效  

Effects of risperidone on psychotic symptoms and others in aged patients with dementia

作　　者：白雪光[1] 黄永兰[1] 刘忠纯[1] 张春香[1] 

机构地区：[1]湖北医科大学附一医院精神科,430060

出　　处：《临床精神医学杂志》2000年第6期340-341,共2页Journal of Clinical Psychiatry

摘　　要：目的 :了解利培酮治疗阿尔茨海默病 (AD)及多发性脑梗死性痴呆 (MID)患者精神病性等症状的疗效。　方法 :对 11例 AD和 10例 MID住院患者在治疗前、治疗后 4周 ,采用简易智能状态检查 (MMSE)及老年临床评定量表 (SCAG)进行评定、比较。　结果 :应用利培酮治疗中发现 ,利培酮用量小 ,治疗后 MMSE总分明显增加 ,SCAG各项因子分明显改善。　结论 :利培酮治疗AD及 MID的精神病性等症状疗效肯定。Objective:In order to study the therapeutic effect of risperidone on psychotic symptoms of Alzheimer disease (AD) and multi infarct dementia (MID). Method:11 patients with AD and 10 patients with MID were tested by mini mental state examination (MMSE) and Sandoz clinical assessment geriatric (SCAG) before and after treatment. Results: The total MMSE score increased significantly,while each factor score of SCAG decreased significantly after treatment. Conclusion:It is suggested that risperidone has definite efficacy on psychotic symptoms of AD and MID.

关 键 词：利培酮 阿尔茨海默病 多发性脑梗死性痴呆 

分 类 号：R749.160.5[医药卫生—神经病学与精神病学] R971.4[医药卫生—临床医学]