高级别星形细胞瘤治疗前DTI评估进展  

The state of the art of pre-treatment evaluation of high-grade astrocytoma with DTI

作　　者：高云云[1] 袁涛[1] 全冠民[1] 

机构地区：[1]河北医科大学第二医院影像科,石家庄050000

出　　处：《国际医学放射学杂志》2013年第6期528-532,共5页International Journal of Medical Radiology

摘　　要：高级别星形细胞瘤是脑肿瘤研究中备受关注的疾病之一,目前高级别星形细胞瘤治疗前最主要的评估手段是MRI。MR扩散张量成像(DTI)可根据组织内水分子的扩散特性探测肿瘤的微观结构和病理改变,如肿瘤细胞密度及异型性、瘤周水肿性质及瘤周白质纤维束病理改变。就DTI在高级别星形细胞瘤治疗前级别判断、范围界定、协助制定手术及放疗计划等方面的进展予以综述。High-grade astrocytoma is one of the high-profile cerebral neoplasms. Although conventional MRI remains the major method for pre-treatment evaluation of high-grade astrocytoma at present, its use can be limited by lacking of functional information. Diffusion tensor imaging （DTI）, which based on the self-diffusion of water molecules in tissues, can provide the information about microscopic structures and pathological changes, including tumor cellularity, peritumoral edema and pathological changes of peritumoral white matter fiber tracts. This review focuses on the progress on pre-treatment evaluation of high-grade astrocytoma with DTI, including tumor grading, peritumoral margins, preoperative planning and radiation planning.

关 键 词：星形细胞瘤 级别 浸润 瘤周水肿 扩散张量成像 磁共振成像 

分 类 号：R739.41[医药卫生—肿瘤]