盐酸法舒地尔治疗后循环缺血的临床疗效观察  

Clinical Efficacy of Fasudil Hydrochloride in the Treatment of Posterior Circulation Ischemia

作　　者：肖辉[1] 孙娜[1] 宁倩[1] 李乐军[1] 

机构地区：[1]南京中医药大学连云港附属医院脑病科,江苏省连云港市222000

出　　处：《实用心脑肺血管病杂志》2013年第12期32-33,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的观察盐酸法舒地尔治疗后循环缺血的临床疗效。方法选取我科2012年8月—2013年6月住院治疗的后循环缺血患者60例,将其随机分为治疗组32例和对照组28例。两组均给予基础治疗,治疗组在基础治疗上加用盐酸法舒地尔,疗程均为14 d。结果治疗组总有效率为87.5%(28/32),高于对照组的78.6%(22/28)(P<0.05);治疗后治疗组双侧椎动脉、基底动脉的收缩期末峰流速(VS)、舒张期末峰流速(VD)均高于对照组(P<0.05)。结论盐酸法舒地尔能够改善后循环系统血流动力学指标,对后循环缺血具有良好疗效。Objective To observe the clinical efficacy of Fasudil hydrochloride in the treatment of posterior circulation isehemia. Methods 60 hospitalized patients with posterior circulation ischemia were chosen from August 2012 June 2013, they were randomly divided into treatment group of 32 cases and control group of 28 cases. Patients in both groups were given basic treatment, and patients in the treatment group was given Fasudil hydrochloride extraly, all patients were treated for 14 days. Re- suits The total efficacy of treatment group was 87.5% （28/32）, higher than that of control gq＇oup of 78.6% （22/28） （P 〈 0.05 ） ; After treatment, the end -systolic peak velocity （VS）, end -diastolic peak velocity （VD） of bilateral vertebral artery and basilar artery in the treatment group were higher than those of control group （ P 〈 0. 05 ）. Conclusion Fasudil hydrochlo- ride can improve hemodynamic parameters of posterior circulation system, has good effect in the treatment of posterior circulation ischemia.

关 键 词：盐酸法舒地尔 后循环缺血 治疗结果 

分 类 号：R364.12[医药卫生—病理学]