^(99m)TcMIBI乳腺显像对乳腺肿物良恶性及淋巴结转移的诊断价值  

Value of ^(99m)Tc MIBI scintimammography in the differential diagnosis betwwen benign breast tumor,breast cancer and lymph node involvement

作　　者：郭大斯[1] 王跃涛[2] 鹿存芝[2] 

机构地区：[1]徐州市第四人民医院肿瘤外科,江苏徐州221009 [2]徐州市第四人民医院核医学科,江苏徐州221009

出　　处：《中国癌症杂志》2000年第6期542-544,共3页China Oncology

摘　　要：目的 :探讨99mTc MIBI乳腺显像对乳腺癌及淋巴结转移的诊断价值。方法 :6 8例单侧乳腺肿物的女性患者 ,从病变乳腺对侧的肘静脉注入99mTc MIBI 740MBq ,10min后分别行前位、侧位乳腺显像。结果 :6 8例乳腺肿物患者 ,经病理证实恶性 38例 ,良性 30例。99mTc MIBI乳腺显像阳性共 37例 ,其中乳腺癌 34例 ,乳腺良性肿瘤 3例。99mTc MIBI乳腺显像诊断乳腺癌的灵敏性为 89 5 % ,特异性为 90 % ,阳性预测值为 91 9% ,阴性预测值为87 1% ;38例乳腺癌患者 8例淋巴结转移 ,6例99mTc MIBI显像阳性。结论 :99mTc MIBI乳腺显像可成为诊断乳腺癌及鉴别乳腺肿物良恶性较可靠的无创性方法 。Purpose:To sutdy the clinical value of 99m Tc MIBI scintimammography in the differential diagnosis between breast cancer and benign breast tumor and lymph node involvement. Methods:68 female patients with breast masses underwent 99m Tc MIBI breast scintigraphy. The images were acquired 10 min after injection of 740 MBq 99m Tc MIBI intravenously. The intravenous injection was performed into an antecubital vein in the arm on the side opposite to the breast mass. Results:38 of 68 patients were breast carcinoma, among them 34 were detected using 99m Tc MIBI scintimammography. Of 30 patients with benign lesions, 3 were positive. The sensitivity and specificity of 99m Tc MIBI scintimammography in detecting breast cancer was 89.5% and 90% respectively. 6 of 8 with pathologically proven metastatic lymph node involvement were detected. Conclusions: 99m Tc MIBI scintimammography is a highly sensitive method in the detection of breast cancer. This study also show the potential value of the procedure to detect lymph node mvolvement.

关 键 词：乳腺肿瘤 淋巴结转移 放射性核素显像 

分 类 号：R737.9[医药卫生—肿瘤] R73－34[医药卫生—临床医学]