腮腺多形性腺瘤包膜特征与手术边界的确定  

Capsule characteristics of parotid pleomorphic adenoma and determination of safe surgical margins

作　　者：梁军[1] 荆少红[2] 吴振婵[3] 游云华[1] 

机构地区：[1]中山大学附属第五医院口腔颌面外科,广东珠海519000 [2]江门市中心医院口腔科,广东江门529000 [3]中山大学附属第五医院骨科,广东珠海519000

出　　处：《中国口腔颌面外科杂志》2013年第6期477-481,共5页China Journal of Oral and Maxillofacial Surgery

基　　金：广东省医学科研基金(B2012146)

摘　　要：目的:研究腮腺多形性腺瘤包膜特征与安全手术边界,为临床治疗提供病理学依据。方法:选择53例腮腺多形性腺瘤术后连续病理切片,镜下观察肿瘤包膜情况,对肿瘤包膜内浸润、伪足及卫星结节的深度进行测量。采用SPSS 16.0软件包对数据进行统计学分析。结果:腮腺多形性腺瘤的包膜特征与其术后复发密切相关,肿瘤包膜内浸润、伪足及卫星结节包膜侵袭的最大及平均距离分别为0.846 mm、(0.399±0.150)mm,1.692 mm、(0.737±0.365)mm,2.369 mm、(1.448±0.635)mm;肿瘤包膜不完整、包膜浸润、伪足及卫星结节与肿瘤大小无显著相关性(P>0.05)。结论:腮腺多形性腺瘤包膜外5 mm以上范围为手术安全切除边界,可达到根治效果。PURPOSE： To study the capsule characteristics of parotid pleomorphic adenoma and determine safe surgical margins for clinical reference based on pathological examination. METHODS： Fifty-three patients with parotid pleomorphic adenoma underwent parotidectomy. Their postoperative serial pathological sections were observed under microscope for capsule changes. The intracapsular infiltration, pseudopodia and satellite nodules depth were measured and analyzed with SPSS 16.0 software package. RESULTS： The capsule characteristics of parotid pleomorphic adenoma were closely related to its recurrence. The maximum and mean invasion distance of intracapsular infiltration, pseudopodia and satellite nodules were 0.846 mm, （0.399_＋0.150） ram; 1.692 mm, （0.737_＋0.365） mm; 2.369 ram, （1.448_＋0.635） mm, respectively. There was no relation between tumor size and capsular characteristics （P〉0.05）.

关 键 词：腮腺 多形性腺瘤 腺体部分切除术 包膜特征 安全手术边界 

分 类 号：R739.8[医药卫生—肿瘤]