睾丸肿瘤的影像表现与肿瘤标记物及病理对照分析  

Imaging features of testicular tumors and the relationship with tumor markers and immunohistochemisty

作　　者：陈明旺[1] 江新青[1] 郭永梅[1] 黄云海[1] 魏新华[1] 

机构地区：[1]广州医学院附属广州市第一人民医院放射科,广东广州510180

出　　处：《实用放射学杂志》2013年第12期1979-1982,1991,共5页Journal of Practical Radiology

摘　　要：目的探讨不同病理类型睾丸肿瘤的特征性影像表现，及其与肿瘤标记物、免疫组化结果的关系。方法24例患者行CT检查，2例患者行MR检查，分析影像学特征并将影像结果与肿瘤标记物及术后病理、免疫组化对照分析。结果16例生殖细胞瘤中包括精原细胞瘤9例，非精原类生殖细胞瘤7例。此外还包括淋巴瘤4例，睾丸转移瘤1例，睾丸支持细胞瘤2例，间皮瘤1例，表皮样囊肿2例。2例精原细胞瘤β-人绒毛膜促性腺激素（β-HCG）和（或）甲胎蛋白（AFP）稍升高。6例非精原生殖细胞瘤伴有pHCG和（或）AFP的明显升高。免疫组化结果AFP、HCG、胎髓碱性磷酸酶（placental alkaline phosphatase，PLAP）、CD117在不同肿瘤中不同表达。结论不同病理类型的睾丸肿瘤有相对特征的影像学表现，结合血清肿瘤标记物检测及免疫组化结果有助于提高诊断准确率。Objective To study the imaging features of different types of testicular tumors, and to find out the relationship among these features and tumor markers and immunohistochemisty, Methods 24 cases were performed CT scan and 2 cases were per formed MR scan. Imaging characters were analyzed and compared with clinical tumor markers and pathology resuhs. Results 16 ca ses of germ cell tumors（GCT）, there were 9 cases of seminoma and 7 cases of nonseminomatous germ cell tumors（NSGCT）. Be sides, there were 4 cases of testicular lymphoma, 1 case of metastatic tumor, 2 cases of sertoli ceils tumor, 1 case of benign meso thelioma, 2 cases of epidermoid cyst. 2 cases of seminoma have a mild increase of 13 human chorionic gonadotropin （β-HCG） and （or） Alpha fetal protein（AFP）. 6 cases of NSGCT have a notable increase of β-HCG and （or） AFP. The expression of AFP,HCG, PLAP,CD117 were various in different type of tumors. Conclusion Each type of testicular tumors has relative characteristic imaging features. Comparing these features with tumor markers and immunohistochemisty, we could make more accurate diagnosis.

关 键 词：睾丸肿瘤 肿瘤标记物 病理 免疫组织化学 

分 类 号：R737.21[医药卫生—肿瘤] R446.6[医药卫生—临床医学]