小肾癌肾脏作为供肾应用于临床肾移植的荟萃分析  

A systematic review for donor kidneys after resection of small renal cancer

作　　者：俞能旺[1] 付帅[1] 王晓菲[1] 郝俊文[1] 张爱民[1] 李香铁[1] 

机构地区：[1]中国人民解放军济南军区总医院泌尿外科,济南250031

出　　处：《中华器官移植杂志》2013年第12期733-736,共4页Chinese Journal of Organ Transplantation

基　　金：中国博士后科学基金（2012M521931）

摘　　要：目的通过检索和分析相关文献，荟萃相关证据，系统评价小肾癌供肾移植的效果及移植后肿瘤复发风险。方法通过制定完备的检索策略，在PubMed、Embase、Cochrane Library和Clinical Trials．gov四个数据库中无语言限制地检索相关文献，人工检索入选文献，避免遗漏。2名研究者根据预先制定好的文献纳入和排除标准独立地筛选文献，按预制好的表格提取纳人文献中的相关资料，数据获取后，汇编成表，计算总的肿瘤复发率。结果共有1680篇文献被检索出，通过筛选，最终纳入15个研究，这15个研究均为病例报道或病例系列研究。通过对现有文献的系统综述，目前总共有96例小肾癌肾脏作为供肾用于临床肾移植，移植后受者均未出现肾癌复发或转移。结论小肾癌供肾用于移植后可获得良好的移植效果，肾癌的复发率相对很低，值得进一步深入研究和应用。Objective kidneys with small renal To review the literature cancer as donor kidneys. and synthesize current evidence on the use of Method To locate eligible studies, four bibliographic databases including PubMed, Embase, Cochrane Library and ClinicalTrials. gov were screened, while key informants were collected and bibliographies of included studies were scrutinised. Two reviewers independently assessed studies for inclusion, extracted data. Data were synthesised as a narrative review. Results 1680 articles were found while eventually 15 studies were selected for this systematic review. All of the 15 included studies were ease reports or case series. Totally 96 documented cases of donor kidneys after resection of small renal cancer were transplanted and no definite recurrence happened. Conclusion It is suggested from current limited evidence that cancer recurrence rate of allotransplanting kidney after resection of SRC was relatively low, thus it deserved much more well-designed clinical trials and clinical use.

关 键 词：肾移植 肾癌 供者 系统评价 

分 类 号：R737.11[医药卫生—肿瘤]