BP素对中晚期肺癌、胃癌及肝癌的疗效观察  

Clinical Study on Median Advanced Lung Cancer, Stomach Cancer and Liver Cancer Treated by BP

作　　者：李学哲[1] 朴惠顺[2] 

机构地区：[1]延边大学附属医院肿瘤部,吉林延吉133000 [2]延边大学药学院,吉林延吉133000

出　　处：《中国医药指南》2013年第33期8-9,共2页Guide of China Medicine

摘　　要：目的观察免疫核糖核酸II(BP素)对中晚期肺癌,胃癌及肝癌患者近期疗效及生活质量的影响。方法根据患者能力及要求分别为单纯化疗组,单纯BP组,BP素联合化疗组,分析治疗疗效,并通过Karnofsky评分了解患者生活质量。结果三种中晚期癌症患者中单纯化疗组与单纯应用BP素组无显著性差异P>0.05。而BP素联合化疗组稳定率明显高于化疗组及BP素组,以肺癌,胃癌为主,分别具有统计学意义P<0.05。三种中晚期癌应用BP素及BP素联合化疗组的生活质量分别明显高于化疗组P<0.05。结论 BP素是一种高效,低毒的生物调节剂,具有抑制肿瘤细胞,增强化疗疗效,减少副反应提高生存质量的作用。Objective To evaluated the therapeutic effect of BP on patients with median advanced lung cancer, stomach cancer and liver cancer. Methods 123 cases of malignant tumors were divided into three groups. Those are regular chemotherapy, BP and BP in combination with chemotherapy. Results There was no signiifcance between the group of chemotherapy and the BP in median advanced cancer（P〉0.05）.The effective of BP combined with chemotherapy was much better than the chemotherapy and BP, especially in lung cancer and stomach cancer respectively（P〈0.05）.And the use of BP can improve the life quality of the patients respectively（P〈0.05）.Conclusion BP combined with chemotherapy can reduce the side reactions of chemotherapy and improve the effect of treatment.

关 键 词：BP素 肿瘤 中晚期 化疗 生活质量 

分 类 号：R734.2[医药卫生—肿瘤] R735.2[医药卫生—临床医学]