喉癌组织中微血管密度与预后的关系  

Study on the relationship between microvascular density and prognosis in laryngeal cancer

作　　者：鲁裕玉[1] 沈朋[1] 丁伟[2] 

机构地区：[1]浙江大学医学院附属第一医院耳鼻咽喉科,杭州310003 [2]浙江大学医学院附属第一医院病理科

出　　处：《临床耳鼻咽喉科杂志》2000年第12期538-539,共2页Journal of Clinical Otorhinolaryngology

摘　　要：目的 :探讨喉癌微血管密度与喉癌预后的关系。方法 :应用 F8相关抗体以 SABC法对 31例手术切除的喉癌微血管进行定量检测。结果 :微血管在喉癌组织学分级及分型中差异无显著性意义 (P >0 .0 5 ) ,而微血管在 2年后的淋巴结转移组 (10 .2 3± 0 .78)与无淋巴结转移组 (6 .38± 0 .33)中差异有显著性意义 (P <0 .0 5 )。结论 :喉癌间质内微血管生成与淋巴结转移和患者的预后有关。Objective:To study the relationship between the microvascular density(MVD) and the prognosis in laryngeal cancer.Method:Microvessel quantitation in 31 cases of laryngeal cancer was done with factorⅧ related antibody and SABC method.Result:The quantitation of microvessels in laryngeal cancer were negative of histologic grade and type, but were signfieantly different (P< 0.05 ) between metastasis ( 10.23 ± 0.78 ) and without metastasis( 6.38 ± 0.33 ) two years after operation.Conclusion:The angiogenesis of laryngeal cancer is correlated with the lymph node metastasis and prognosis.

关 键 词：喉肿瘤 微血管密度 淋巴结转移 预后 

分 类 号：R739.650.7[医药卫生—肿瘤]