全麻复合硬膜外麻醉在食管癌手术中的临床价值分析  

Analysis on the Clinical Value of General Combined Epidural Anesthesia in Esophageal Cancer Surgery

作　　者：刘晓兵[1] 许宇红[2] 王建[2] 朱轶华 马霞[1] 

机构地区：[1]如东县第三人民医院麻醉科,江苏如东226406 [2]南通市第一人民医院麻醉科,江苏南通226001

出　　处：《肿瘤药学》2013年第6期455-458,共4页Anti-Tumor Pharmacy

摘　　要：目的探讨全身麻醉复合硬膜外麻醉在食管癌手术中的临床应用价值。方法选取58例食管癌择期手术患者并将其随机分为观察组和对照组。观察组29例,先行硬膜外穿刺置管后再行气管内插管全麻;对照组29例,仅用全身麻醉。观察和比较两组患者围麻醉期的平均动脉压(MAP)、心率(HR)、术后苏醒时间、苏醒质量和拔管时间。结果两组患者的麻醉前(H0)MAP、HR的差异无统计学意义,H1、H2、H3、H4四个时间点的MAP和HR比较,差异有统计学意义(P<0.05);观察组术中自主呼吸恢复、拔管和定向力恢复时间均明显短于对照组(P<0.05)。结论静脉全麻加硬膜外阻滞麻醉应用于食管癌手术的麻醉效果好,能减少麻醉药物使用量,且患者术后恢复较快。Objective To investigate the chmcal value of general combined epidural anesthesia during operation of esophageal carcinoma. Methods Fifty-eight patients with carcinoma of esophagus were randomly divided into observation group （n=29） and control group （n=29）. The observation group had general combined with epidural anesthesia and the control group only had general anesthesia. The mean artery pressure （MAP）, heart rate （HR）, time of postoperative revival and extubation were recorded and compared. Results The difference of MAP and HR between the two groups had no statistical meaning before anesthesia （H0）, but had statistical significance at the time points of ill, H2, H3 and H4 （P〈0.05）. Patients in observation group took shorter time to get autonomous respiration, extubation and orientation regaining than those in control group （P〈0.05）. Conclusion General combined epidural anesthesia had good effects during operation of esophageal carcinoma. It could lessen the dose of anaesthetic and render patients take shorter time to get recovery.

关 键 词：全身麻醉 硬膜外麻醉 食管癌 

分 类 号：R735.1[医药卫生—肿瘤]