宫颈上皮内瘤变发生的相关危险因素分析  

Analysis of risk factors related to the occurrence of cervical intraepithelial neoplasia

作　　者：李莉[1] 于红[2] 王蓓[3] 

机构地区：[1]江苏省疾病预防控制中心性病艾滋病防治所,江苏南京210009 [2]东南大学附属中大医院妇产科,江苏南京210009 [3]东南大学公共卫生学院,江苏南京210009

出　　处：《中国医药导报》2013年第25期123-124,127,共3页China Medical Herald

基　　金：国家自然科学基金(编号30872156)

摘　　要：目的调查分析宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)发生的相关危险因素。方法对入组的148例宫颈疾病患者(包括CIN组105例和宫颈炎组43例)通过问卷调查的形式采集相关资料分析CIN发生的相关危险因素。结果经单因素非条件Logistic回归分析,首次性生活年龄、妊娠次数、性生活频率和性生活前清洗习惯这4项因素差异有统计学意义(P<0.05);多因素非条件Logistic回归分析结果显示,妊娠次数>3次是CIN发生的危险因素(P<0.05),性生活前双方清洗阴部是CIN发生的保护因素(P<0.05)。结论加强女性的健康保健意识、性行为时积极采取安全保护措施可能会降低CIN的发生率。Objective To survey and analyze the risk factors related to the occurrence of cervical intraepithelial neoplasia （CIN）.Methods The data of 148 cases of patients with cervical disease （including 43 cases of chronic cervicitis group and 105 cases of CIN group） were collected by questionnaire to analyze the risk factors related to the occurrence of CIN.Results The results of single factor unconditional Logistic regression analysis showed that the age of first sexual life,times of pregnancy,the frequency of sexual life and cleaning habits before sexual life had statistical significance （P ＜ 0.05）.Multi-factor unconditional Logistic regression analysis showed that pregnancy more than 3 times was a risk factor of the occurrence of CIN （P ＜ 0.05）,cleaning pudenda both before sexual life was a protective factor of the occurrence of CIN （P ＜ 0.05）.Conclusion Strengthening female health care consciousness and actively taking safety precautions during sexual intercourse may reduce the incidence of CIN.

关 键 词：宫颈上皮内癌变 宫颈炎 危险因素 LOGISTIC回归 

分 类 号：R737.33[医药卫生—肿瘤]