烤瓷熔附金属冠颈缘位置对龈沟液中内毒素及天冬氨酸基转移酶表达的影响  

Effects of the marginal position of porcelain-fused-to-metal crown on gingival crevicular fluid volume and endotoxin aspartate transaminase levels

作　　者：彭蓓[1] 季娟娟[1] 杨杨[1] 黄大海[1] 张晓渝[1] 王祥芸[1] 

机构地区：[1]云南省第二人民医院口腔科,昆明650021

出　　处：《国际口腔医学杂志》2014年第1期16-19,共4页International Journal of Stomatology

基　　金：云南省科技厅-昆明医学院联合专项基金(2009cd187)

摘　　要：目的探讨烤瓷熔附金属(PFM)冠边缘位置对牙周健康的影响。方法将因下颌第一磨牙牙体缺损要求采用镍铬合金PFM冠修复的60例患者随机分成2组,并根据冠的颈缘位置不同分为A组(龈下)和B组(平龈)。分别测定并分析基牙修复前和修复后1、3、6个月龈沟液(GCF)量及其中内毒素和天冬氨酸基转移酶(AST)的含量变化。结果与修复前相比,A组龈沟内的GCF量及其内毒素和AST的含量在冠修复1、3、6个月后明显增加,差异有统计学意义(P<0.05),而B组的差异无统计学意义(P>0.05);同时,两组之间比较,在GCF量、内毒素和AST的平均含量上,在修复后相同时间段的差异有统计学意义(P>0.05)。结论烤瓷冠颈缘位置对牙周健康有一定影响,平龈的设计明显优于龈下设计。Objective This study aims to investigate the effect of the marginal position of porcelain-fused-to-metal（PFM） crown on periodontal health. Methods Sixty patients who needed PFM crown for the mandibular first molar were randomly divided into two groups of 30 patients each according to the difference in the marginal position of the crown. Group A comprised patients with crown margins under the gingival level, whereas Group B was composed of patients with crown margin at the gingival level. Gingival crevicular fluid（GCF） were collected at four time points, namely, before crown cementation and at 1, 3, and 6 months after crown cementation. GCF volume, endotoxin levels, and aspartate transaminase（AST） were detected using an automated chemical analyzer. The differences among the variations between pre- and post-crown cementation and between the two groups were analyzed. Results GCF volume, endotoxin levels, and AST in Group A increased at 1, 3, and 6 months after cementation compared with that before crown cementation（P〈0.05）. In Group B, the GCF volume, endotoxin levels, and AST remained stable and did not exhibit any changes（P〉0.05）. Significant statistical differences were found between the means of variation of Groups A and B at 1, 3, and 6 months after cementation（P〈0.05）. Conclusion Based on the results of this study, the PFM crown with gingival margin at gingival level is better than that under gingival level in terms of its benefit to periodontal health.

关 键 词：烤瓷熔附金属冠 冠颈缘位置 龈沟液 内毒素 天冬氨酸基转移酶 

分 类 号：R783[医药卫生—口腔医学]