减肥保健食品中添加化学药物的快速检测方法研究  

Study on the Rapid Identification of Adulterants in Health Food with Weight Reducing Function

作　　者：万林春 王栋 丁银平 郑盈莹 

机构地区：[1]江西省食品药品检验所,南昌330029

出　　处：《中国药事》2013年第12期1285-1290,共6页Chinese Pharmaceutical Affairs

基　　金：江西省科技支撑计划--保健食品中非法添加化学药物快速检测系统研究(编号:2009BGA03100)

摘　　要：目的建立薄层色谱法和液相色谱-质谱联用法检测常见减肥类保健食品中添加的化学药。方法运用薄层色谱法快速初筛,液相色谱-质谱联用法定性鉴定的色谱光谱综合运用技术。结果建立的方法能够系统而快速地鉴别出添加的盐酸西布曲明、盐酸芬氟拉明、酚酞、士的宁、盐酸麻黄碱、氢氯噻嗪等化学药物成分。结论本方法准确可靠、简便易行,易于推广。Objective To develop a method for the identification of adulterants in health food with weight reducing function by TLC and HPLC-MS-MS.Methods TLC and HPLC-MS-MS were adopted.After TLC screening,the adulterants were confirmed by HPLC-MS-MS.Results Sibutramine hydrochloride,fenfluramine hydrochloride,phenolphthalein,strychnine,ephedrine hydrochloride,hydrochlorothiazide were identified by this method.Conclusion The method is precise,reliable,simple,rapid and can be used universally for the identification of adulterants in slimming foods.

关 键 词：保健食品 薄层色谱 液相色谱-质谱联用 盐酸西布曲明 盐酸芬氟拉明 酚酞 士的宁 盐酸麻黄碱 氢氯噻嗪 

分 类 号：R917[医药卫生—药物分析学]