81例儿童患者EB病毒感染用药分析  

Investigation of drugs use in 81 EB vrius infection pediatric patients

作　　者：王健康[1] 董晓莉[1] 陈孝果[1] 丁志强[1] 王力宏[1] 

机构地区：[1]解放军空军总医院药学部,北京100142

出　　处：《临床药物治疗杂志》2013年第6期35-37,46,共4页Clinical Medication Journal

摘　　要：目的:分析我院儿童患者EB病毒感染用药特点,并对反映出的问题进行探讨。方法:采用回顾性研究方法,主要对2009-2010年度我院确诊的EB病毒感染患儿抗病毒药物和抗生素药物的种类、剂量、疗程及联合用药等指标进行分析。结果:患儿主要在血液科和儿科收治,多达86.4%的患者并发多系统感染。抗病毒药物主要采用更昔洛韦、阿昔洛韦和利巴韦林;抗生素主要采用第二代或第三代头孢菌素。对于EB病毒感染患儿,存在首诊确诊率低、更昔洛韦用药时间较长等现象。结论:对于儿童EB病毒感染,抗病毒用药仍需规范并须循证医学证据支持;同时应提高首诊确诊率。Objective： To study the status quo and characteristics of drugs use in EB vrius Infection pediatric patients in our hospital, and to discuss the problems occurred in the drugs use. Methods： The use of antibiotics and antiviral drugs in EB virus infection pediatric patients in our hospital in 2009-2010 were collected, and category, dosage, treatment time and combination of antibiotics were retrospectively analyzed. Results： Most of pediatric patients were treated in department of hematology and pediatrics. Multisystemic concurrent infection occurred in over 86.4% pediatric patients. The antiviral drugs such as ganciclovir, acyclovir, ribavirin and the antibiotics such as II or Ill generation cephalosporin were adopted. But there were the phenomenon of too long treatment time using ganciclovir and exists low rate of final diagnosis at first time. Conclusion： For children patients with EB virus infection, Use of antiviral drugs should be standard and get the support of further clinical evidences. The final diagnosis rate at first time also should be promoted.

关 键 词：临床药学 EB病毒感染 抗生素 抗病毒药物 合理用药 

分 类 号：R537.4[医药卫生—内科学] R734.1[医药卫生—临床医学]