植酸改性对AZ31镁合金表面细胞黏附性能的影响  

Effect of phytic acid modification AZ31magnesium alloy on the cell surface adhesion property

作　　者：杨旭[1] 李兰兰[1] 贺建[1] 乔丽英[2] 

机构地区：[1]第三军医大学化学教研室,重庆400038 [2]重庆大学材料科学与工程学院,重庆400044

出　　处：《重庆大学学报（自然科学版）》2013年第11期33-37,共5页Journal of Chongqing University

基　　金：重庆市科技攻关计划资助项目(CSCT2010AB5116);国家自然科学基金青年基金资助项目(51101174);高等学校博士学科点专项科研基金资助项目(20100191120014)

摘　　要：用浸没法在AZ31镁合金表面制备植酸涂层,用携带能谱仪的扫描电子显微镜研究了表面涂层的化学组成和形貌,并用直接法和间接法分别在植酸改性前后的镁合金表面培养细胞,检测细胞存活率,考查人骨肉瘤细胞在植酸改性前后镁合金表面的黏附能力。结果表明:在镁合金表面形成均匀的植酸涂层,植酸改性前后镁合金对细胞存活率影响相近,但细胞在植酸改性前后镁合金表面的黏附能力存在显著差异,植酸改性可有效改善AZ31镁合金的细胞黏附性能。Phytic acid coatings on the surface of AZ31 magnesium alloys are prepared by immersion method. Then cell culture and detection of cell survival rate on treated or untreated AZ31 magnesium alloy with phytic acid is carried out by tile direct method and the indirect method respectively,and surface morphology and chemical composition of coatings are studied by scanning electron microscopy with energy dispersive spectrometer. The results show that uniform phytic acid coating forms on the surface of magnesium alloy, and there is a similar cell survival rate on the treated or untreated AZ31 magnesium alloy surface. But the adhesive ability of cells on the surface of phytic acid modification magnesium alloy is significantly different. Phytic acid modification can effectively improve the cell adhesion properties of AZ31 magnesium alloy.

关 键 词：植酸改性 AZ31镁合金 细胞 黏附性能 

分 类 号：R318.08[医药卫生—生物医学工程]