脑心通胶囊联合阿托伐他汀对脑梗死颈动脉粥样硬化患者的治疗效果分析  

The Clinical Effect Analysis of Combined Application of Naoxintong Capsule and Atorvastatin in the Treatment of Cerebral Infarction with Carotid Artery Atherosclerosis

作　　者：朱长东[1] 刘南海[1] 吕志迈[2] 

机构地区：[1]赣南医学院第二附属医院,江西赣州341600 [2]赣南医学院第一附属医院

出　　处：《中国医学创新》2013年第35期8-10,共3页Medical Innovation of China

摘　　要：目的:探讨脑心通胶囊联合阿托伐他汀对脑梗死颈动脉粥样硬化患者的治疗效果。方法:以本院2010年1月-2013年1月间收治的脑梗死合并有颈动脉粥样硬化患者150例为研究对象,按照随机数字表法将其分为观察组和对照组各75例。对照组使用阿司匹林、阿托伐他汀钙片,观察组在此基础上增加使用脑心通胶囊,比较两组患者治疗后体内脂类代谢情况、粥样硬化情况和同型半胱氨酸水平。结果:观察组总胆固醇、血清甘油三酯和低密度脂蛋白胆固醇含量低于对照组,颈动脉内膜-中层厚度、斑块面积和Hcy含量小于对照组,两组比较差异均有统计学意义(P<0.05)。结论:使用脑心通胶囊联合阿托伐他汀治疗方案可以提高脑梗死合并颈动脉粥样硬化患者临床治疗效果,降低脑梗死复发危险和粥样硬化程度。Objective： To investigate the effect of combined application of Naoxintong capsule and atorvastatin in the treatment of cerebral infarction with carotid artery atherosclerosis.Mcthod： One hundred and fifty patients with cerebral infarction and carotid artery atheroselerosis were divided into the objective group and the control group, each group of 75 cases. The aspirin and atorvastatin were used in the control group and the Naoxintong capsule was added in the objective group. The lipid metabolism and the level of atherosclerosis and Hey were compared between the two groups.Result： TC, TG, LDL-C, IMT, plaque area and the level of Hcy after the treatment of the objective group were lower than those of the control group, and HDL-C of the objective group was higher than the ones of the control group, and the difference between the two groups were statistically significant （ P〈0.05 ） . Conclusion： It can get a satisfaction effect for combined application of Naoxintong capsule and atorvastatin in the treatment of cerebral infarction with carotid artery atherosclerosis.

关 键 词：脑心通胶囊 脑梗死 动脉粥样硬化 

分 类 号：R743.33[医药卫生—神经病学与精神病学]