壳聚糖Cu(Ⅱ)、Zn(Ⅱ)配合物的合成及性能研究  

STUDY OF SYNTHESIS AND PROPERTIES ON CHITOSAN-CU(Ⅱ) AND CHITOSAN-ZN(Ⅱ) COMPLEX

作　　者：赵宇[1] 张东真[1] 张璇[1] 伍华昌 毕彩丰[1] 

机构地区：[1]中国海洋大学化学化工学院教育部重点实验室

出　　处：《海洋湖沼通报》2013年第4期125-129,共5页Transactions of Oceanology and Limnology

基　　金：国家大学生创新性实验计划(2007SR11)专项资助

摘　　要：将铜、锌离子与壳聚糖(CTS)通过配位反应合成壳聚糖铜、锌配合物,考察了脱乙酰度、温度对产品中金属含量的影响。测定了产物的缓释性能、抑菌性能及除氧活性。结果表明配合物在人工海水中15d的累积释放率为0.76%,说明了其具有优异的缓释性能。壳聚糖金属铜、锌配合物对枯草杆菌和四链球菌都具有良好的抑制作用,第10d抑菌率可达到55%,CTS-Cu(Ⅱ)比CTS-Zn(Ⅱ)对O2·-抑制效果更为明显,配合物的浓度越高,其清除活性氧的能力越强。Chitosan-Zn and chitosan-Cu complexes were synthesized. The effect of degree of deacetyla- tion and temperature on the metal content was studied. The property of slow release, anti-bacteria and anti-oxidation of products were measured. The results showed that the release rate of complexes in artificial seawater was 0.76% in 15d. It presented the outstanding property of slow release of the complexes. Chitosan-Zn and chitosan-Cu complexes showed significant effect against Bacillus subtilis and Micrococcus tetragenus. The anti-bacteria rate of complexes was 55% at 10th day. The inhibition rate increased with the increasing of concentration of complexes, and CTS- Cu Ⅱ ） complex showed the highest inhibition activity than CTS- Zn （ Ⅱ ）.

关 键 词：聚糖 壳聚糖配合物 缓释 抑菌性 除氧活性 

分 类 号：P734[天文地球—海洋化学]