重症急性胰腺炎合并胃肠功能障碍的机制研究及诊治现状  

Severe acute pancreatitis complicated with gastrointestinal dysfunction: Pathogenesis, diagnosis and treatment

作　　者：刘丽蕾[1] 王湘英[2] 

机构地区：[1]南华大学,湖南省衡阳市421001 [2]湖南省人民医院重症监护室,湖南省长沙市410005

出　　处：《世界华人消化杂志》2013年第34期3828-3834,共7页World Chinese Journal of Digestology

基　　金：湖南省科技计划基金资助项目;No.2012SK3242~~

摘　　要：重症急性胰腺炎(severe acute pancreatitis,SAP)常合并胃肠功能紊乱,导致胃肠动力障碍,甚至引起胃肠功能衰竭,对SAP病程和预后有着重要的影响,是导致SAP患者死亡的重要原因,直接影响着重症急性胰腺炎本身的治疗效果和预后,为判定重症急性胰腺炎预后的重要指标之一.本文旨在通过文献复习总结SAP合并胃肠功能障碍的病理生理学变化、发病机制及当前的诊治进展.Severe acute pancreatitis （SAP） is often associated with gastrointestinal dysfunction, leading to gas- trointestinal motility disorders and even gastroin- testinal failure, which has an important effect on SAP progression and prognosis, directly influences the outcome of treatment, is an important cause of death in patients with SAP, and moreover, has been one of the important prognostic factors for SAP. This review aims to discuss the pathophysiol- ogy, pathogenesis, diagnosis and treatment of SAP with gastrointestinal dysfunction.

关 键 词：重症急性胰腺炎 胃肠动力 炎性因子 胃肠激素 胰腺炎相关性腹水 

分 类 号：R576[医药卫生—消化系统]