Voltammetric quantitation of nitazoxanide by glassy carbon electrode  

作　　者：Rajeev Jain Rajeev Kumar Yadav Jahangir Ahmad Rather 

机构地区：[1]School of Studies in Chemistry,Jiwaji University

出　　处：《Journal of Pharmaceutical Analysis》2013年第6期452-455,共4页药物分析学报（英文版）

摘　　要：The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson （B-R） buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 ~tg/mL. The limit of detection （LOD） and limit of quantification （LOQ） was calculated to be 5.23 la~/mL and 17.45 la~/mL, respectively.The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson （B-R） buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 ~tg/mL. The limit of detection （LOD） and limit of quantification （LOQ） was calculated to be 5.23 la~/mL and 17.45 la~/mL, respectively.

关 键 词：NITAZOXANIDE Squarewave voltammetry Glassy carbon electrode Pharmaceuticalformulation 

分 类 号：O657.1[理学—分析化学] O657.14[理学—化学]