声触诊组织量化技术对乳腺小占位的定性诊断价值  

Diagnostic value of virtual touch tissue quantification in discriminating the small breast lesions

作　　者：孟洁[1] 纪晓惠[1] 刘明瑜[1] 韩若凌[1] 

机构地区：[1]河北医科大学第四医院超声科,石家庄050011

出　　处：《中华超声影像学杂志》2013年第12期1053-1055,共3页Chinese Journal of Ultrasonography

基　　金：河北省卫生厅医学科学研究重点课题计划（20120127）

摘　　要：目的探讨声触诊组织量化（VTQ）技术对乳腺内小占位性病变的鉴别诊断价值。方法对56例69个乳腺内小占位性病变（病灶最大径≤1cm）进行VTQ检测，测量病灶及周围正常腺体组织的剪切波速度（swv），对比良性组与恶性组swV的平均值（Vm）、病灶与正常腺体组织SwV之比（Vml／Vm2），分析良、恶性病灶SwV的差异，绘制ROC曲线找出swV预测小乳腺癌的最佳截点。结果良性组vrn、Vml／Vm2分别为（2．93±1．32）m／s、1．79±0．63，恶性组分别为（5．65±2．63）m／s、3．61±1．35，上述参数良性组与恶性组之间差异具有统计学意义（P〈0．05）。以Vm值4．43m／s作为诊断恶性病变的截点，其灵敏度为80．5％，特异度为89．3％，准确度为92．8％；以Vml／Vm2值2．37作为诊断恶性病变的截点，其灵敏度为76．9％，特异度为81．2％，准确度为89．9％。结论VTQ技术对于乳腺内≤1cm的小病灶具有较高的鉴别诊断价值。Objective To evaluate the application value of virtual touch tissue quantification（VTQ） in the differential diagnosis of small breast lesions. Methods Fifty-six patients with sixty-nine small breast lesions whose largest diameter were less than or equal to i cm were evaluated with VTQ. The shear wave velocity （SWV） of the lesions and normal breast tissue were measured to analyze the diversity of different pathological types lesions of SWV and to find the optimal cut-off points using ROC curve to predict small breast cancer. Results The mean SWV（Vm） and the ratio （mean of lesions and normal tissue） of SWV （Vml/Vm2） in benign group was （2.93 ± 1.32）m/s, 1.79 ± 0.63, respectively,and that in malignant group was （5.65 ± 2.63） m/s, 3.61 ± 1.35, respectively, there were statistically significant differences between benign group and malignant group （ t test, P〈0.05）. The cut-off point of Vm was determined as 4.43 m/ s,the sensitivity, specificity and accuracy of diagnosing breast cancer were 80.5%, 89.3%, 92.8%, respectively. The cut-off point of Vml/Vm2 was determined as 2. 37, the sensitivity, specificity and accuracy of diagnosing breast cancer were 76.9%, 81.2%,89.9%, respectively. Conclusions VTQ technique can provide helpful information in the differential diagnosis of small breast lesions.

关 键 词：超声检查 乳腺疾病 声触诊组织量化 

分 类 号：R737.9[医药卫生—肿瘤]