三维能量多普勒超声对宫颈癌的诊断价值  

Value of three-dimensional power Doppler ultrasound in diagnosis of cervical cancers

作　　者：刘微[1] 孙立涛[1] 刘娜娜[1] 王珍珍[1] 窦新颖[1] 孔宪超[1] 

机构地区：[1]哈尔滨医科大学附属第二医院超声科,150086

出　　处：《中华超声影像学杂志》2013年第12期1056-1059,共4页Chinese Journal of Ultrasonography

基　　金：黑龙江省教育厅2013年度科学技术研究（面上）项目（12531250）

摘　　要：目的探讨三维能量多普勒超声（three-dimensional power Doppler ultrasound，3D PDUS）对宫颈癌的诊断价值。方法分析162例宫颈病变患者的3D PDUS图像，所有病例均经手术或组织活检病理证实。获得宫颈病变患者的三维血管参数，以病理结果为金标准比较良恶性病变的三维血管参数，采用ROC曲线分析三维血管参数在鉴别宫颈良恶性病变中的最佳截断值。结果宫颈良恶性病变的三维血管参数差异具有统计学意义（P〈0．0001）。ROC曲线显示当选取血管指数为4．63时，曲线下面积最大达0．94，特异性和灵敏性分别为86．30％和89．10％；当血流指数为34．39时，曲线下面积最大达0．76，特异性和灵敏性分别为76．70％和73．40％；当血管血流指数为1．60时，曲线下面积最大达0．93，特异性和灵敏性分别为86．30％和87．50％。结论3D PDUS为宫颈良恶性病变的鉴别诊断提供了一种新的无创性检查方法。Objective To evaluate the clinical value of three-dimensional power Doppler ultrasound （3D PDUS） in diagnosing cervical cancers. Methods 162 patients with cervical lesions were enrolled. All the cases were confirmed by autopsy or surgery. Vascularization index （VI）, flow index （FI） and vaseularization flow index（VFI） were all measured and compared. The pathological findings was taken as golden standard. ROC curve was used to find the best cut off value. Results 3D PDUS indices of benign and malignant lesions were statistically different （ P〈0. 0001）. The best cut-off value of VI was 4.63 using ROC curves,the area under the curve （AUC） was 0.94, the sensitivity and specificity were 89.10% and 86.30% ,respectively. The best cutoff value of FI was 34.39 using ROC curves, AUC was 0.76, the sensitivity and specificity were 73.40 % and 76.70 %, respectively. The best cut off value of VFI was I. 60 using ROC curves,AUC was 0.93, the sensitivity and specificity were 87.50% and 86.30% , respectively. Conclusions 3D PDUS was a new and noninvasive way for the clinical to differentiate benign and malignant cervical lesions.

关 键 词：超声检查 宫颈肿瘤 

分 类 号：R737.33[医药卫生—肿瘤]